2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate

Base Information

• Chemical Name: 2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate
• CAS No.: 1266134-54-6
• Molecular Formula: C5H10F6N5P
• Molecular Weight: 285.132
• Mol file: 1266134-54-6.mol

Synonyms:2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate;2-Azido-4,5-dihydro-1,3-dimethyl-1H-imidazolium hexafluorophosphate

Chemical Property of 2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate

Chemical Property:

• Melting Point: 205-210°C
• PSA: 69.59000
• LogP: 2.97226
• Storage Temp.: ?20°C

Purity/Quality:

97% ^*data from raw suppliers

2-Azido-1,3-dimethylimidazolinium hexafluorophosphate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Efficient diazo transfer reagent for the preparation of azides from primary amines. An alternative to tosyl azide with an easier-to-separate water soluble by-product.

Technology Process of 2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate

There total 2 articles about 2-Azido-1,3-diMethyliMidazoliniuM Hexafluorophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-chloro-1,3-dimethyl-2-imidazolinium hexafluorophosphate (101385-69-7) → 2-azido-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate (V) (1266134-54-6)

Guidance literature:

With sodium azide; In acetonitrile; at 0 ℃; for 0.5h;

DOI:10.1055/s-0030-1258457

Reference yield:

1,3-dimethyl-2-imidazolidinone (80-73-9) → 2-azido-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate (V) (1266134-54-6)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl dichloride / toluene / 3 h / 50 °C / Inert atmosphere

2: sodium hexaflorophosphate / acetonitrile / 0.5 h / 20 °C / Inert atmosphere

3: sodium azide / acetonitrile / 3 h / 0 °C / Inert atmosphere

With sodium hexaflorophosphate; sodium azide; oxalyl dichloride; In toluene; acetonitrile;

DOI:10.1002/anie.201406694

Reference yield: 97.0%

2-azido-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate (V) (1266134-54-6) + 2-phenyl-1-p-tolyl-ethanone (2001-28-7) → C20H23N3O (1309977-00-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; acetonitrile; at 0 ℃; for 1.5h;

DOI:10.1016/j.tetlet.2011.04.042

upstream raw materials:

2-chloro-1,3-dimethyl-2-imidazolinium hexafluorophosphate

1,3-dimethyl-2-imidazolidinone

Downstream raw materials:

C₁₉H₂₁N₃O

C₂₀H₂₃N₃O₂

C₂₂H₂₇N₃O

C₁₄H₁₉N₃O