2-CHLORO-4,6-DIIODOANILINE

Base Information

• Chemical Name: 2-CHLORO-4,6-DIIODOANILINE
• CAS No.: 89280-97-7
• Molecular Formula: C6H4ClI2N
• Molecular Weight: 379.366
• Mol file: 89280-97-7.mol

Synonyms:2-CHLORO-4,6-DIIODOANILINE

Chemical Property of 2-CHLORO-4,6-DIIODOANILINE

Chemical Property:

• PSA: 26.02000
• LogP: 3.71260

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-CHLORO-4,6-DIIODOANILINE

There total 3 articles about 2-CHLORO-4,6-DIIODOANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

o-chloroaniline (95-51-2) → 2-chloro-4,6-diiodoaniline (89280-97-7)

Guidance literature:

With iodine; silver sulfate; In ethanol; at 25 ℃; for 24h;

DOI:10.1071/CH13324

Reference yield: 64.0%

2-chloro-4-iodoaniline (42016-93-3) → 2-chloro-4,6-diiodoaniline (89280-97-7)

Guidance literature:

With N-iodo-succinimide; In N,N-dimethyl-formamide; at 50 ℃; for 288h; Cooling with ice;

Reference yield: 61.0%

o-chloroaniline (95-51-2) → 2-chloro-4-iodoaniline (42016-93-3) + 2-chloro-4,6-diiodoaniline (89280-97-7)

Guidance literature:

With hydrogenchloride; sodium iodine dichloride; In methanol; water; at 20 ℃; for 3h; pH=1 - 2;

DOI:10.1080/00304948.2016.1206425

upstream raw materials:

o-chloroaniline

2-chloro-4-iodoaniline

Downstream raw materials:

1-chloro-2,3,5-triiodobenzene

Refernces

• 1、 Elmi, Shire,Heggen, Per,Holmelid, Bjarte,Malthe-S?rensen, Didrik,Sydnes, Leiv K.. "Iodination of Anilines with Sodium Dichloroiodate". . p. 385 - 392. Retrieved 2016/09/14.