Iso Methadone

Base Information

Chemical Name:Iso Methadone
CAS No.:14474-54-5
Molecular Formula:C21H28N2
Molecular Weight:308.46042
Hs Code.:
Mol file:14474-54-5.mol

Synonyms:UNII-W5198OQ7X1;Iso Methadone Ketimine;4-Imino-N,N,2-trimethyl-3,3-diphenyhexylamine;Isomethadon-ketimin;6-Dimethylamino-5-methyl-4.4-diphenyl-hexan-3-on-imin;6-dimethylamino-5-methyl-4,4-diphenyl-hexan-3-one-imine;

Suppliers and Price of Iso Methadone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Iso Methadone

Chemical Property:

Boiling Point:471.4±45.0 °C(Predicted)
PKA:9.34±0.70(Predicted)
PSA：27.09000
Density:0.95±0.1 g/cm3(Predicted)
LogP:4.69990

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An intermediate of Isomethadone (Isoamidone).

Technology Process of Iso Methadone

There total 4 articles about Iso Methadone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6293-01-2
2,2-diphenyl-3-methyl-4-(dimethylamino)-butyronitrile

: 925-90-6
ethylmagnesium bromide

: 14474-54-5
6-dimethylamino-5-methyl-4,4-diphenyl-hexan-3-one-imine

Guidance literature:: With diethyl ether; xylene; Behandeln des Reaktionsgemisches mit wss. Salzsaeure;
DOI:10.1039/jr9490000648 DOI:10.1021/ja01202a061 DOI:10.1021/ja01181a023

Reference yield:

: 86-29-3
Diphenylacetonitrile

: 14474-54-5
6-dimethylamino-5-methyl-4,4-diphenyl-hexan-3-one-imine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate; tert-butyl alcohol; xylene / Erwaermen des Reaktionsgemisches mit (+-)-Dimethyl-<2-chlor-propyl>-amin

2: diethyl ether; xylene / Behandeln des Reaktionsgemisches mit wss. Salzsaeure

With diethyl ether; potassium tert-butylate; xylene; tert-butyl alcohol;
DOI:10.1021/ja01202a061

Reference yield:

: 140-29-4
phenylacetonitrile

: 14474-54-5
6-dimethylamino-5-methyl-4,4-diphenyl-hexan-3-one-imine

Guidance literature:: Multi-step reaction with 3 steps

1: bromine / 105 - 110 °C / Erwaermen des Reaktionsgemisches mit Benzol und Aluminiumchlorid

2: potassium tert-butylate; tert-butyl alcohol; xylene / Erwaermen des Reaktionsgemisches mit (+-)-Dimethyl-<2-chlor-propyl>-amin

3: diethyl ether; xylene / Behandeln des Reaktionsgemisches mit wss. Salzsaeure

With diethyl ether; potassium tert-butylate; bromine; xylene; tert-butyl alcohol;
DOI:10.1021/ja01202a061