N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE

Base Information

• Chemical Name: N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE
• CAS No.: 99918-43-1
• Molecular Formula: C11H16N2.2ClH
• Molecular Weight: 249.183
• Mol file: 99918-43-1.mol

Synonyms:N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE;4-(N-PhenylaMino)piperidine, diHCl;4-(phenylamino)piperidine 2HCl;N-Phenylpiperidin-4-yl-amine 2HCl

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE

Chemical Property:

• PSA: 24.06000
• LogP: 3.85630

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE is a useful research chemical.

Technology Process of N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE

There total 3 articles about N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(tert-butoxycarbonyl)-4-phenylaminopiperidine (125541-22-2) → N-phenylpiperidin-4-amine dihydrochloride (99918-43-1)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃;

Reference yield:

N-tert-butyloxycarbonylpiperidin-4-one (79099-07-3) → N-phenylpiperidin-4-amine dihydrochloride (99918-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid / dichloromethane / 0.5 h / 20 °C

1.2: 0 °C

2.1: hydrogenchloride / ethanol / 20 °C

With hydrogenchloride; acetic acid; In ethanol; dichloromethane;

Reference yield:

aniline (62-53-3) → N-phenylpiperidin-4-amine dihydrochloride (99918-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid / dichloromethane / 0.5 h / 20 °C

1.2: 0 °C

2.1: hydrogenchloride / ethanol / 20 °C

With hydrogenchloride; acetic acid; In ethanol; dichloromethane;

upstream raw materials:

1-(tert-butoxycarbonyl)-4-phenylaminopiperidine

N-tert-butyloxycarbonylpiperidin-4-one

aniline

Downstream raw materials:

[2-(Imino-phenyl-methyl)-phenyl]-piperidin-4-yl-amine

Refernces