4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline

Base Information

• Chemical Name: 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline
• CAS No.: 1160474-88-3
• Molecular Formula: C17H28N4
• Molecular Weight: 288.436
• Hs Code.: 2933599090
• Mol file: 1160474-88-3.mol

Synonyms:4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline;1-[2-Amino-5-(4-methylpiperazin-1-yl)phenyl]-4-methylpiperidine, 1-[4-Amino-3-(4-methylpiperidin-1-yl)phenyl]-4-methylpiperazine

Chemical Property of 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline

Chemical Property:

• Boiling Point: 476.6±45.0 °C(Predicted)
• PKA: 10.50±0.13(Predicted)
• PSA: 35.74000
• Density: 1.079±0.06 g/cm3(Predicted)
• LogP: 2.90600

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Methylpiperazino)-2-(4-methylpiperidino)aniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline

There total 4 articles about 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-methyl-4-(3-(4-methylpiperidin-1-yl)-4-nitrophenyl)piperazine (885704-49-4) → 4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)aniline (1160474-88-3)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; methanol; water; at 90 ℃; for 1h; Reflux;

Reference yield:

4-chloro-2-fluoro-nitrobenzene (700-37-8) → 4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)aniline (1160474-88-3)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / 0.67 h / 0 - 23 °C

2: 12 h / 138 °C / Inert atmosphere

3: ammonium chloride; zinc / tetrahydrofuran; methanol; water / 1 h / 90 °C / Reflux

With ammonium chloride; zinc; In tetrahydrofuran; methanol; ethanol; water;

Reference yield:

4-methylpiperidin (626-58-4) → 4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)aniline (1160474-88-3)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol / 0.67 h / 0 - 23 °C

2: 12 h / 138 °C / Inert atmosphere

3: ammonium chloride; zinc / tetrahydrofuran; methanol; water / 1 h / 90 °C / Reflux

With ammonium chloride; zinc; In tetrahydrofuran; methanol; ethanol; water;

upstream raw materials:

1-methyl-4-(3-(4-methylpiperidin-1-yl)-4-nitrophenyl)piperazine

4-chloro-2-fluoro-nitrobenzene

4-methylpiperidin

1-(5-chloro-2-nitrophenyl)-4-methylpiperidine

Downstream raw materials:

4-cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1160474-88-3 4-(4-Methylpiperazino)-2-(4-methylpiperidino)-aniline

Send

Send

Metric Ton KG G Pound L ML

Send

Send