Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI)

Base Information

Chemical Name:Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI)
CAS No.:868235-18-1
Molecular Formula:C₂₅H₂₂N₂O₈S
Molecular Weight:510.524
Hs Code.:
Mol file:868235-18-1.mol

Synonyms:Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI);4'-Thiouridine 5'-acetate 2',3'-dibenzoate

Suppliers and Price of Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI)

Chemical Property:

PKA:9.39±0.10(Predicted)
Density:1.45±0.1 g/cm3(Predicted)

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI)

There total 2 articles about Uridine, 4'-thio-, 5'-acetate 2',3'-dibenzoate (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1,5-di-O-acetyl-2,3-di-O-benzoyl-4-deoxy-4-thio-D-xylofuranose

: 66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6
uracil

: 868235-18-1
N¹-(5-O-acetyl-2,3-di-O-benzoyl-4-deoxy-4-thio-β-D-xylofuranos-1-yl)uracil

Guidance literature:: uracil; In acetonitrile; at 80 ℃; for 0.75h; Inert atmosphere;

1,5-di-O-acetyl-2,3-di-O-benzoyl-4-deoxy-4-thio-D-xylofuranose; With tin(IV) chloride; In acetonitrile; at 40 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2020.115645

Reference yield:

: 15076-96-7
C₂₇H₂₄O₇S

: 868235-18-1
N¹-(5-O-acetyl-2,3-di-O-benzoyl-4-deoxy-4-thio-β-D-xylofuranos-1-yl)uracil

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid

2.1: N,O-bis-(trimethylsilyl)-acetamide / acetonitrile / 2 h / 60 °C

2.2: 0.5 h / 0 - 60 °C

With N,O-bis-(trimethylsilyl)-acetamide; sulfuric acid; In acetonitrile;
DOI:10.1021/jacs.8b12565