5-Methyl-2-(4-methyl-1-piperazinyl)aniline

Base Information

Chemical Name:5-Methyl-2-(4-methyl-1-piperazinyl)aniline
CAS No.:946731-22-2
Molecular Formula:C₁₂H₁₉N₃
Molecular Weight:205.303
Hs Code.:2933599090
DSSTox Substance ID:DTXSID60589745
Wikidata:Q82483298
Mol file:946731-22-2.mol

Synonyms:946731-22-2;5-METHYL-2-(4-METHYL-1-PIPERAZINYL)ANILINE;5-methyl-2-(4-methylpiperazin-1-yl)aniline;SCHEMBL8710759;DTXSID60589745;BBL035023;STL411940;AKOS000101717;VS-12821

Suppliers and Price of 5-Methyl-2-(4-methyl-1-piperazinyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-methyl-2-(4-methyl-1-piperazinyl)aniline
50mg
$ 130.00

TRC
5-methyl-2-(4-methyl-1-piperazinyl)aniline
10mg
$ 60.00

TRC
5-methyl-2-(4-methyl-1-piperazinyl)aniline
5mg
$ 45.00

Matrix Scientific
5-Methyl-2-(4-methyl-1-piperazinyl)aniline
2.5g
$ 720.00

Matrix Scientific
5-Methyl-2-(4-methyl-1-piperazinyl)aniline
500mg
$ 237.00

AK Scientific
5-Methyl-2-(4-methyl-1-piperazinyl)aniline
2.5g
$ 1022.00

Total 6 raw suppliers

Chemical Property of 5-Methyl-2-(4-methyl-1-piperazinyl)aniline

Chemical Property:

Vapor Pressure:4.37E-05mmHg at 25°C
Boiling Point:350.5°C at 760 mmHg
PKA:8.42±0.40(Predicted)
Flash Point:163.4°C
PSA：32.50000
Density:1.073g/cm³
LogP:1.91310
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:205.157897619
Heavy Atom Count:15
Complexity:199

Purity/Quality:

98%min ^*data from raw suppliers

5-methyl-2-(4-methyl-1-piperazinyl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)N2CCN(CC2)C)N

Technology Process of 5-Methyl-2-(4-methyl-1-piperazinyl)aniline

There total 2 articles about 5-Methyl-2-(4-methyl-1-piperazinyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-01-3
1-methyl-piperazine

: 946731-22-2
2-(4-methylpiperazin-1-yl)-5-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 12 h / 122 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 5 h / 20 °C / 760.05 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol; dimethyl sulfoxide;
DOI:10.1021/acs.jmedchem.7b00468

Reference yield:

: 446-11-7
4-fluoro-3-nitrotoluene

: 946731-22-2
2-(4-methylpiperazin-1-yl)-5-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 12 h / 122 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 5 h / 20 °C / 760.05 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol; dimethyl sulfoxide;
DOI:10.1021/acs.jmedchem.7b00468

Reference yield:

: 946731-22-2
2-(4-methylpiperazin-1-yl)-5-methylaniline

: N-(5-methyl-2-(4-methylpiperazin-1-yl)phenyl)-N'-(4-(3-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / tetrahydrofuran; N,N-dimethyl-formamide / 3 h / 20 °C

2: 1-Methylpyrrolidine / 1,4-dioxane / 12 h / 80 °C

With 1-Methylpyrrolidine; pyridine; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00468