[1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester

Base Information

• Chemical Name: [1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester
• CAS No.: 91896-97-8
• Molecular Formula: C₁₆H₂₄O₄
• Molecular Weight: 280.364
• Mol file: 91896-97-8.mol

Synonyms:(-)-Epizafronic acid methyl ester;[1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester;Epizafronic acid methyl ester

Chemical Property of [1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester

Chemical Property:

• Melting Point: 175 - 178 °C
• PSA: 66.76000
• LogP: 1.81990

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester

There total 1 articles about [1R,(-)]-1,2,3,4,4aα,7,8,8aα-Octahydro-4α,6α-dihydroxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + methyl (9S)2-acetylepizafronate (91896-96-7) → (9S) methyl epizafronate (91896-97-8)

Guidance literature:

Multistep reaction; 1.) saponification;

DOI:10.1016/S0040-4020(01)88464-7

upstream raw materials:

diazomethane

methyl (9S)2-acetylepizafronate