(R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid

Base Information

Chemical Name:(R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid
CAS No.:92471-85-7
Molecular Formula:C14H13BrO3
Molecular Weight:309.159
Hs Code.:
Mol file:92471-85-7.mol

Synonyms:(R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid;(-)-BroMonaproxen;(R)-5-BroMo Naproxen;R-(-)-2-(5-BroMo-6-Methoxy-2-naphthyl)propionic Acid

Suppliers and Price of (R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-5-BromoNaproxen
250mg
$ 1320.00

Total 3 raw suppliers

Chemical Property of (R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid

Chemical Property:

Boiling Point:446.2±30.0 °C (760 mmHg)
PSA：46.53000
Density:1.483±0.06 g/cm3 (20 °C, 760 mmHg)
LogP:3.79900

Purity/Quality:: (R)-5-BromoNaproxen ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (R)-5-Bromo Naproxen is an impurity of (R)-Naproxen (N377510).

Technology Process of (R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid

There total 5 articles about (R)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2S,3R)-2-[2-(5-Bromo-6-methoxy-naphthalen-2-yl)-propionyloxy]-3-hydroxy-succinic acid diethyl ester

: 84236-26-0
S-(+)-2-(5-Bromo-6-Methoxy-2-Naphthyl)-Propionic Acid

: 92471-85-7
2(R)-(-)-(5-bromo-6-methoxy-2-naphthyl)propanoic acid

Guidance literature:: With hydrogenchloride; water; acetic acid; at 85 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo00390a013

Reference yield:

: (2S,3R)-2-[2-(5-Bromo-6-methoxy-naphthalen-2-yl)-propionyloxy]-3-hydroxy-succinic acid diisopropyl ester

: 84236-26-0
S-(+)-2-(5-Bromo-6-Methoxy-2-Naphthyl)-Propionic Acid

: 92471-85-7
2(R)-(-)-(5-bromo-6-methoxy-2-naphthyl)propanoic acid

Guidance literature:: With hydrogenchloride; water; acetic acid; at 85 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1021/jo00390a013

Reference yield:

: 866365-36-8
2-(5-bromo-6-methoxy-naphthalen-2-yl)-propionic acid ethyl ester

: (S)-2-(5-Bromo-6-methoxy-naphthalen-2-yl)-propionic acid ethyl ester

: (R)-2-(5-Bromo-6-methoxy-naphthalen-2-yl)-propionic acid ethyl ester

: 84236-26-0
S-(+)-2-(5-Bromo-6-Methoxy-2-Naphthyl)-Propionic Acid

: 92471-85-7
2(R)-(-)-(5-bromo-6-methoxy-2-naphthyl)propanoic acid

Guidance literature:: With Candida cylindraceae lipase; In phosphate buffer; at 30 ℃; for 105h; pH=8.0; Title compound not separated from byproducts;
DOI:10.1016/j.tetasy.2005.07.009