4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane

Base Information

• Chemical Name: 4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane
• CAS No.: 89854-94-4
• Molecular Formula: C7H15NO
• Molecular Weight: 129.202
• Hs Code.: 2922190090
• Mol file: 89854-94-4.mol

Synonyms:(4-Aminocyclohex-1-yl)methanol;4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane;trans-4-(Hydroxymethyl)-cyclohexylamine

Chemical Property of 4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane

Chemical Property:

• PSA: 46.25000
• LogP: 1.19650

Purity/Quality:

97% ^*data from raw suppliers

(4-Aminocyclohexyl)methanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane

There total 8 articles about 4-(Hydroxymethyl)cyclohexan-1-amine, 1-Amino-4-(hydroxymethyl)cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitrobenzaldehdye (555-16-8) → 4-aminobenzaldehyde (556-18-3,28107-09-7) + 4-aminocyclohexylmethanol (89854-94-4)

Guidance literature:

With hydrogen; In water; at 50 ℃; for 6h; under 3750.38 Torr; Autoclave;

DOI:10.1016/j.apcata.2020.117536

Reference yield:

4-nitro-benzoic acid (62-23-7) → 4-aminocyclohexylmethanol (89854-94-4)

Guidance literature:

With hydrogen; In water; at 220 ℃; for 24h; under 37503.8 Torr; Autoclave;

DOI:10.1016/j.jcat.2021.05.013

Reference yield:

4-nitrobenzaldehdye (555-16-8) → 4-aminocyclohexylmethanol (89854-94-4)

Guidance literature:

With hydrogen; In ethanol; at 100 ℃; for 10h; under 22502.3 Torr; Autoclave;

DOI:10.1016/j.apcata.2020.117536

upstream raw materials:

ethyl 4-(hydroxyimino)cyclohexane-1-carboxylate

4-hydroxyimino-cyclohexanecarboxylic acid

methyl trans-4-amino-cyclohexanecarboxylate

4-nitrobenzaldehdye

Downstream raw materials:

N-(4-(hydroxymethyl)cyclohexyl)isonicotinamide

4-amino-5-((4-(isonicotinamido)cyclohexyl)methoxy)-2-methylquinoline-3-carboxylic acid

ethyl 4-amino-5-((4-(isonicotinamido)cyclohexyl)methoxy)-2-methylquinoline-3-carboxylate

N-(4-((3-amino-2-cyanophenoxy)methyl)cyclohexyl)isonicotinamide