Mandelamide, o-bromo- (8CI)

Base Information

• Chemical Name: Mandelamide, o-bromo- (8CI)
• CAS No.: 21165-17-3
• Molecular Formula: C8H8BrNO2
• Molecular Weight: 230.06
• Mol file: 21165-17-3.mol

Synonyms:Mandelamide, o-bromo- (8CI)

Chemical Property of Mandelamide, o-bromo- (8CI)

Chemical Property:

• Melting Point: 97.5 °C
• Boiling Point: 123-126 °C
• PKA: 12.05±0.20(Predicted)
• PSA: 63.32000
• Density: 1.673±0.06 g/cm3(Predicted)
• LogP: 1.66810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Mandelamide, o-bromo- (8CI)

There total 2 articles about Mandelamide, o-bromo- (8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(2-bromophenyl)-2-hydroxyacetonitrile (52923-21-4,1269472-47-0,548478-30-4) → o-bromo mandelamide (21165-17-3)

Guidance literature:

With silver trifluoromethanesulfonate; C₃₃H₃₃ClO₇P₃Pt⁽¹⁺⁾*CF₃O₃S^(1-); In tetrahydrofuran; water; at 23 ℃; Catalytic behavior;

DOI:10.1021/acscatal.1c02254

Reference yield:

→ o-bromo mandelamide (21165-17-3)

Guidance literature:

o-bromo mandelic acid methylester, dry NH3 gas;

upstream raw materials:

2-(2-bromophenyl)-2-hydroxyacetonitrile

Refernces