Chemical Property of Digitin
Chemical Property:
- Appearance/Colour:white crystalline powder
- Melting Point:230-240 °C (dec.)(lit.)
- Refractive Index:-52 ° (C=1, EtOH)
- Boiling Point:788.4°C (rough estimate)
- PKA:12.68±0.70(Predicted)
- PSA：454.67000
- Density:1.59 g/cm3
- LogP:-6.50450
- Storage Temp.:Store at RT.
- Solubility.:H2O: 10 mg/mL at 95 °C hot, clear, colorle
- XLogP3:-3.9
- Hydrogen Bond Donor Count:17
- Hydrogen Bond Acceptor Count:29
- Rotatable Bond Count:14
- Exact Mass:1228.57242689
- Heavy Atom Count:85
- Complexity:2230
- Purity/Quality:
-
99%, *data from raw suppliers
Digitonin *data from reagent suppliers
Safty Information:
- Pictogram(s):
T
- Hazard Codes:T
- Statements:
23/24/25
- Safety Statements:
22-28-36/37-45
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Chemical Classes:Other Uses -> Biochemical Research
- Canonical SMILES:CC1CCC2(C(C3C(O2)C(C4C3(CCC5C4CCC6C5(CC(C(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)OC9C(C(C(CO9)O)O)O)OC2C(C(C(C(O2)CO)O)OC2C(C(C(C(O2)CO)O)O)O)O)O)O)O)C)C)O)C)OC1
- Isomeric SMILES:C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)[C@H]([C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@@H]6[C@@]5(C[C@H]([C@@H](C6)O[C@H]7[C@@H]([C@H]([C@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@H](C([C@H](O8)CO)O)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O)O)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O)C)C)O)C)OC1
-
Uses
enhances membrane permeability Natural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells Clinical reagent (cholesterol determination). Digitonin has been used in a study to assess a procedure for isolating mitochondria from ascites tumor cells. It has also been used in a study to investigate its effect on the cytotoxicity of plant secondary metabolites in cancer cells. This mild nonionic detergent can be used to solubilize receptors and permeabilize cellular and nuclear membranes.
