BICALUTAMIDE-D4

Base Information

• Chemical Name: BICALUTAMIDE-D4
• CAS No.: 1185035-71-5
• Molecular Formula: C18H10D4F4N2O4S
• Molecular Weight: 434.4
• Mol file: 1185035-71-5.mol

Synonyms:BICALUTAMIDE-D4;Casodex-d4;ICI-176334-d4;N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4;(CI-176334-D4

Chemical Property of BICALUTAMIDE-D4

Chemical Property:

• Melting Point: 192-1940C
• PSA: 119.13000
• LogP: 4.60988
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)

Purity/Quality:

> 95% ^*data from raw suppliers

Bicalutamide-d4 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.
• Uses: BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0