tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Base Information

Chemical Name:tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate
CAS No.:1108745-86-3
Molecular Formula:C₁₇H₂₂F₃N₃O₃
Molecular Weight:373.375
Hs Code.:

Synonyms:tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Suppliers and Price of tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

There total 6 articles about tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 942468-37-3
tert-butyl 2-nitro-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

: 1108745-86-3
tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 16h; under 760.051 Torr;

Reference yield: 85.0%

: 942468-37-3
tert-butyl 2-nitro-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

: 407-25-0
trifluoroacetic anhydride

: 1108745-86-3
tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 16h;

Reference yield:

: 942468-36-2
tert-butyl 2-nitro-4-(piperazin-1-yl)benzoate

: 1108745-86-3
tert-butyl 2-amino-4-(4-(2,2,2-trifluoroacetyl)piperazin-1-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: palladium on activated charcoal; hydrogen / methanol / 16 h / 20 °C / 760.05 Torr

With palladium on activated charcoal; hydrogen; triethylamine; In methanol; dichloromethane;