Indanazoline hydrochloride

Base Information

• Chemical Name: Indanazoline hydrochloride
• CAS No.: 40507-80-0
• Deprecated CAS: 56601-85-5
• Molecular Formula: C12H16ClN3
• Molecular Weight: 237.732
• Hs Code.: 2933290090
• European Community (EC) Number: 254-945-0
• UNII: Z364A90IV8
• DSSTox Substance ID: DTXSID20960910
• Wikidata: Q27294933
• NCI Thesaurus Code: C97700
• Mol file: 40507-80-0.mol

Synonyms:E-VA-16;Farial;indanazolin;indanazoline;indanazoline hydrochloride;indanazoline monohydrochloride;indanazoline mononitrate;N-(2,3-dihydro-1H-indan-4-yl)-2,5-dihydro-1H-imidazol-2-amine;N-(2-imidazolin-2-yl)-N-(4-indanyl)amine

Chemical Property of Indanazoline hydrochloride

Chemical Property:

• Vapor Pressure: 0.00018mmHg at 25°C
• Melting Point: 182-184°
• Boiling Point: 329.2°Cat760mmHg
• Flash Point: 152.9°C
• PSA: 36.42000
• Density: 1.3g/cm³
• LogP: 2.18580
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 237.1032752
• Heavy Atom Count: 16
• Complexity: 262

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1)C(=CC=C2)NC3=NCCN3.Cl

Technology Process of Indanazoline hydrochloride

There total 2 articles about Indanazoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

N-4-Indanyl-S-methyl-isothioharnstoff (40507-79-7) + ethylene diamine mono-p-toluenesulfonic acid salt (14034-59-4,7294-10-2) → Indanazolin-monohydrochlorid (40507-80-0)

Guidance literature:

With hydrogenchloride; In various solvent(s); at 130 - 135 ℃; for 5h;

Reference yield:

→ Indanazolin-monohydrochlorid (40507-80-0)

Guidance literature:

N-4-Indanyl-S-methyl-isothioharnstoff + Ethylendiamin-mono-p-toluol-sulfonat.;

Reference yield:

Indanazolin-monohydrochlorid (40507-80-0) → 4-aminoindan (32202-61-2)

Guidance literature:

In water; at 20 ℃; Mechanism; pH 1, 3, 5, 7, 8; other temperatures; stability; investigations in different buffer mixtures (pH-values); chemical stability and light stability;

upstream raw materials:

N-4-Indanyl-S-methyl-isothioharnstoff

ethylene diamine mono-p-toluenesulfonic acid salt

Downstream raw materials:

4-aminoindan