Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1

Base Information

Chemical Name:Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1
CAS No.:909035-22-9
Molecular Formula:C₁₃H₁₆ClNO*ClH
Molecular Weight:274.19
Hs Code.:
Mol file:909035-22-9.mol

Synonyms:Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1;(+/-)-4-aMine-1'-Boc-3,4-dihydro-6-Methoxyspiro (2H-1-benzopyran-2,4'-piperidine);Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride;6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine] hydrochloride

Suppliers and Price of Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1

Chemical Property:

PSA：21.26000
LogP:3.91800

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1

There total 5 articles about Spiro[2H-1-benzopyran-2,4'-piperidine], 6-chloro-3,4-dihydro-, hydrochloride (1:1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 644968-53-6
1'-benzyl-6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine]

: 909035-22-9
6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine] hydrochloride

Guidance literature:: 1'-benzyl-6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine]; With carbonochloridic acid 1-chloro-ethyl ester; In toluene; Heating / reflux;

In methanol; Heating / reflux;

Reference yield: 29.0%

: 909035-22-9
6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine] hydrochloride

Guidance literature:

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 909035-22-9
6-chloro-3,4-dihydrospiro[chromene-2,4'-piperidine] hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyrrolidine / methanol / 3 h / 70 °C

2.1: aluminum (III) chloride; N-tert-butylaminoborane / dichloromethane / 0.25 h / 0 °C

2.2: 5 h / 0 - 20 °C

3.1: carbonochloridic acid 1-chloro-ethyl ester / toluene / Heating / reflux

3.2: Heating / reflux

With pyrrolidine; aluminum (III) chloride; carbonochloridic acid 1-chloro-ethyl ester; N-tert-butylaminoborane; In methanol; dichloromethane; toluene;