16-Epikopsinine

Base Information

• Chemical Name: 16-Epikopsinine
• CAS No.: 28161-78-6
• Molecular Formula: C₂₁H₂₆N₂O₂
• Molecular Weight: 338.45
• Mol file: 28161-78-6.mol

Synonyms:3-Isokopsinine(8CI); Aspidofractinine-3-carboxylic acid, methyl ester, (2a,3a,5a)-; 16-Epikopsinine

Chemical Property of 16-Epikopsinine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16-Epikopsinine

There total 22 articles about 16-Epikopsinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C34H34N2O4S (1320267-57-9) → kopsinine (559-51-3,28161-78-6,98737-06-5,98759-78-5)

Guidance literature:

With Raney Ni; In ethanol; at 78 ℃;

DOI:10.1038/nature10232

Reference yield:

C27H28N2O3 (1320267-61-5) → kopsinine (559-51-3,28161-78-6,98737-06-5,98759-78-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: trimethylsilyl iodide; triethylamine / dichloromethane / 0 °C

1.2: 40 °C

1.3: 0 °C

2.1: triethylamine / toluene / -45 - 23 °C

2.2: -30 - 23 °C

2.3: 0 °C

3.1: benzene / 100 °C

4.1: Raney Ni / ethanol / 78 °C

With trimethylsilyl iodide; triethylamine; In ethanol; dichloromethane; toluene; benzene;

DOI:10.1038/nature10232

Reference yield:

C24H22N2 → kopsinine (559-51-3,28161-78-6,98737-06-5,98759-78-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / toluene / -45 - 23 °C

1.2: -30 - 23 °C

1.3: 0 °C

2.1: benzene / 100 °C

3.1: Raney Ni / ethanol / 78 °C

With triethylamine; In ethanol; toluene; benzene;

DOI:10.1038/nature10232

upstream raw materials:

C₂₁H₂₄N₂O₂S

5-oxokopsinic acid

C₂₇H₂₈N₂O₃

C₂₆H₂₆N₂O₂