4,5-Dichloro-6-(trifluoromethyl)pyrimidine

Base Information

Chemical Name:4,5-Dichloro-6-(trifluoromethyl)pyrimidine
CAS No.:141602-36-0
Molecular Formula:C5HCl2F3N2
Molecular Weight:216.978
Hs Code.:2933599590
DSSTox Substance ID:DTXSID30476613
Mol file:141602-36-0.mol

Synonyms:4,5-Dichloro-6-(trifluoromethyl)pyrimidine;141602-36-0;4,5-DICHLORO-6-TRIFLUOROMETHYLPYRIMIDINE;4,5-Dichloro-6-trifluoromethyl-pyrimidine;SCHEMBL2424060;DTXSID30476613;AB54866;CS-0446219;Pyrimidine, 4,5-dichloro-6-(trifluoromethyl)-

Suppliers and Price of 4,5-Dichloro-6-(trifluoromethyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4,5-Dichloro-6-(trifluoromethyl)pyrimidine 95%
1 g
$ 576.00

SynQuest Laboratories
4,5-Dichloro-6-(trifluoromethyl)pyrimidine 95%
250 mg
$ 288.00

SynQuest Laboratories
4,5-Dichloro-6-(trifluoromethyl)pyrimidine 95%
5 g
$ 1152.00

Crysdot
4,5-Dichloro-6-(trifluoromethyl)pyrimidine 95+%
1g
$ 788.00

Chemenu
4,5-dichloro-6-(trifluoromethyl)pyrimidine 95%
1g
$ 745.00

Apolloscientific
4,5-Dichloro-6-(trifluoromethyl)pyrimidine
5g
$ 1044.00

Apolloscientific
4,5-Dichloro-6-(trifluoromethyl)pyrimidine
250mg
$ 261.00

Apolloscientific
4,5-Dichloro-6-(trifluoromethyl)pyrimidine
1g
$ 522.00

American Custom Chemicals Corporation
4,5-DICHLORO-6-TRIFLUOROMETHYLPYRIMIDINE 95.00%
5MG
$ 498.18

Total 3 raw suppliers

Chemical Property of 4,5-Dichloro-6-(trifluoromethyl)pyrimidine

Chemical Property:

Boiling Point:217.9±35.0 °C(Predicted)
PKA:-6.14±0.28(Predicted)
PSA：25.78000
Density:1.627±0.06 g/cm3(Predicted)
LogP:2.80220
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:215.9468879
Heavy Atom Count:12
Complexity:163

Purity/Quality:

98%min ^*data from raw suppliers

4,5-Dichloro-6-(trifluoromethyl)pyrimidine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C(C(=N1)Cl)Cl)C(F)(F)F

Technology Process of 4,5-Dichloro-6-(trifluoromethyl)pyrimidine

There total 4 articles about 4,5-Dichloro-6-(trifluoromethyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-chloro-4-hydroxy-6-trifluoromethyl-pyrimidine

: 141602-36-0
4,5-dichloro-6-(trifluoromethyl)pyrimidine

Guidance literature:: With trichlorophosphate; In toluene; Reflux;
DOI:10.1016/j.jfluchem.2017.08.008

Reference yield:

: 5-chloro-6-(trifluoromethyl)pyrimidin-4(3H)-one

: 141602-36-0
4,5-dichloro-6-(trifluoromethyl)pyrimidine

Guidance literature:: With trichlorophosphate; at 100 ℃; for 1.5h;

Reference yield:

: 1546-78-7
4-trifluoromethyl-1,6-dihydropyrimidine-6-oxide

: 141602-36-0
4,5-dichloro-6-(trifluoromethyl)pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 9 h / 50 °C

2: trichlorophosphate / 1.5 h / 100 °C

With N-chloro-succinimide; trichlorophosphate; In N,N-dimethyl-formamide;