(Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene

Base Information

Chemical Name:(Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene
CAS No.:144758-26-9
Molecular Formula:C12H11ClO2
Molecular Weight:222.671
Hs Code.:
DSSTox Substance ID:DTXSID50455445
Nikkaji Number:J1.515.719D
Mol file:144758-26-9.mol

Synonyms:144758-26-9;(CHLOROCARBONYL)(2,4,6-TRIMETHYLPHENYL)KETENE;SCHEMBL7811949;2-mesityl-3-oxoacryloyl chloride;DTXSID50455445;SERXVFRECJWTHE-UHFFFAOYSA-N;(Chloroformyl)(2,4,6-trimethylphenyl)ketene

Suppliers and Price of (Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene

Chemical Property:

PSA：34.14000
LogP:2.59220
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:222.0447573
Heavy Atom Count:15
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C)C(=C=O)C(=O)Cl)C

Technology Process of (Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene

There total 3 articles about (Chlorocarbonyl)(2,4,6-trimethylphenyl)ketene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: mesitylmalonic acid

: 144758-26-9
(chlorocarbonyl)-2,4,6-trimethylphenyl ketene

Guidance literature:: With thionyl chloride; In methyl cyclohexane;

Reference yield:

: 4408-60-0
2-mesitylacetic acid

: 144758-26-9
(chlorocarbonyl)-2,4,6-trimethylphenyl ketene

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 - -30 °C / Inert atmosphere

1.2: 2 h / -78 - 0 °C / Inert atmosphere; Cooling with ice

2.1: thionyl chloride / toluene / 1 h / Reflux

With n-butyllithium; thionyl chloride; In tetrahydrofuran; hexane; toluene;