4-Chloro-2-iodopyridine

Base Information

Chemical Name:4-Chloro-2-iodopyridine
CAS No.:22918-03-2
Molecular Formula:C5H3ClIN
Molecular Weight:239.443
Hs Code.:9999999999
DSSTox Substance ID:DTXSID20463774
Nikkaji Number:J2.023.176I
Wikidata:Q82288804
Mol file:22918-03-2.mol

Synonyms:4-Chloro-2-iodopyridine;22918-03-2;4-chloro-2-iodo-pyridine;Pyridine, 4-chloro-2-iodo-;MFCD12913885;SCHEMBL1542095;AMY6267;DTXSID20463774;GGGYBMCVKQXJBU-UHFFFAOYSA-N;ZB1263;AKOS015966795;CS-W022141;DS-6059;SB35623;SY035610;O11208;A878387

Suppliers and Price of 4-Chloro-2-iodopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-2-iodopyridine
500mg
$ 165.00

SynChem
4-CHLORO-2-IODOPYRIDINE 95%
1 g
$ 550.00

Labseeker
4-Chloro-2-iodopyridine 95
100g
$ 1833.00

J&W Pharmlab
4-Chloro-2-iodo-pyridine 96%
25g
$ 1590.00

J&W Pharmlab
4-Chloro-2-iodo-pyridine 96%
1g
$ 98.00

J&W Pharmlab
4-Chloro-2-iodo-pyridine 96%
500mg
$ 88.00

J&W Pharmlab
4-Chloro-2-iodo-pyridine 96%
250mg
$ 78.00

J&W Pharmlab
4-Chloro-2-iodo-pyridine 96%
5g
$ 398.00

Crysdot
4-Chloro-2-iodopyridine 98%
5g
$ 256.00

Crysdot
4-Chloro-2-iodopyridine 98%
10g
$ 505.00

Total 13 raw suppliers

Chemical Property of 4-Chloro-2-iodopyridine

Chemical Property:

PSA：12.89000
LogP:2.33960
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:238.89987
Heavy Atom Count:8
Complexity:78.8

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-2-iodopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C=C1Cl)I
Uses 4-Chloro-2-iodopyridine is used in the synthetic preparation of disubstituted chloropyridine derivatives by regioselective lithiathion of chloropyridines with butyllithium and dimethylaminoehanol which is then followed by substitution with electrophiles.

Technology Process of 4-Chloro-2-iodopyridine

There total 1 articles about 4-Chloro-2-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 626-61-9
4-Chloropyridine

: 22918-03-2
2-iodo-4-pyridyl chloride

Guidance literature:: 4-Chloropyridine; With n-butyllithium; In hexane; at -78 ℃; for 1h;

With iodine; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1h;
DOI:10.1002/1099-0690(200102)2001:3<603::AID-EJOC603>3.0.CO;2-2

Reference yield: 76.0%

: 22918-03-2
2-iodo-4-pyridyl chloride

: 346656-34-6
2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid ethyl ester

: 681831-93-6
ethyl 2-(4-chloro-2-pyridyl)benzoate

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 18h;
DOI:10.1016/j.tet.2004.01.050