3-(2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-4-YL)PROPIONIC ACID

Base Information

• Chemical Name: 3-(2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-4-YL)PROPIONIC ACID
• CAS No.: 30741-72-1
• Molecular Formula: C12H12N2O4
• Molecular Weight: 248.23468
• Mol file: 30741-72-1.mol

Synonyms:3-(2,5-Dioxo-4-phenyliMidazolidin-4-yl)propanoic acid;2,5-Dioxo-4-phenyl-4-imidazolidinepropionic acid

Chemical Property of 3-(2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-4-YL)PROPIONIC ACID

Chemical Property:

• Melting Point: 215℃
• PKA: 4.37±0.10(Predicted)
• PSA: 102.48000
• Density: 1.341±0.06 g/cm3(Predicted)
• LogP: 0.50200
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(2,5-Dioxo-4-phenyl-imidazolidin-4-yl)-propionic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-4-YL)PROPIONIC ACID

There total 3 articles about 3-(2,5-DIOXO-4-PHENYL-IMIDAZOLIDIN-4-YL)PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanide + ammonium bicarbonate (1066-33-7,6721-33-1,10361-29-2) + succinylbenzene (2051-95-8) → 3-(2,5-dioxo-4-phenylimidazolidin-4-yl)propionic acid (30741-72-1)

Guidance literature:

With ammonia; In ethanol; water; at 60 ℃;

Reference yield:

3-(2,5-dioxo-4-phenyl-imidazolidin-4-yl)-propionitrile → 3-(2,5-dioxo-4-phenylimidazolidin-4-yl)propionic acid (30741-72-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo01156a014

Reference yield:

→ 3-(2,5-dioxo-4-phenylimidazolidin-4-yl)propionic acid (30741-72-1)

Guidance literature:

Benzoylpropionsaeure, KCN, (NH4)2CO3;

upstream raw materials:

ammonium bicarbonate

succinylbenzene

Downstream raw materials:

2-amino-2-phenyl-glutaric acid