5-(2-Methylpropyl)piperazin-2-one

Base Information

Chemical Name:5-(2-Methylpropyl)piperazin-2-one
CAS No.:106607-78-7
Molecular Formula:C₈H₁₆N₂O
Molecular Weight:156.228
Hs Code.:
DSSTox Substance ID:DTXSID60543665
Mol file:106607-78-7.mol

Synonyms:5-(2-METHYLPROPYL)PIPERAZIN-2-ONE;106607-78-7;907973-09-5;Piperazinone, 5-(2-methylpropyl)-, (S)- (9CI);5-Isobutylpiperazin-2-one;5-ISOBUTYL-PIPERAZIN-2-ONE;SCHEMBL24052995;DTXSID60543665;1240589-69-8;AKOS006287500;AB37219;AB37220;AB37224;(R)-5-ISOBUTYL-PIPERAZIN-2-ONE;(S)-5-ISOBUTYL-PIPERAZIN-2-ONE;CS-0459453;EN300-693104

Suppliers and Price of 5-(2-Methylpropyl)piperazin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-(2-Methylpropyl)piperazin-2-one

Chemical Property:

PSA：44.62000
LogP:0.72520
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:156.126263138
Heavy Atom Count:11
Complexity:145

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1CNC(=O)CN1

Technology Process of 5-(2-Methylpropyl)piperazin-2-one

There total 2 articles about 5-(2-Methylpropyl)piperazin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 106576-30-1
ethyl (S)-2-(2-isobutyl-1-aziridinyl)acetate

: 106607-78-7,907973-09-5
5-isobutyl-2-piperazinone

: 2-(2-isobutyl-1-aziridinyl)acetamide

Guidance literature:: With boron trifluoride diethyl etherate; ammonia; for 24h; Ambient temperature; 1.) dry ice-methanol bath; 2.) 95-98 deg C, 24 h;
DOI:10.1246/bcsj.59.321

Reference yield:

: 23852-57-5
(S)-2-(2-Methylpropyl)-aziridine

: 106607-78-7,907973-09-5
5-isobutyl-2-piperazinone

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / triethylamine

2: 42 percent / BF_3.OEt₂, ammonia / 24 h / Ambient temperature; 1.) dry ice-methanol bath; 2.) 95-98 deg C, 24 h

With boron trifluoride diethyl etherate; ammonia; triethylamine;
DOI:10.1246/bcsj.59.321