tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Base Information

Chemical Name:tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate
CAS No.:1345728-58-6
Molecular Formula:C19H30N2O2
Molecular Weight:318.459
Hs Code.:
Mol file:1345728-58-6.mol

Synonyms:tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Suppliers and Price of tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-butylN-[(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate
2.5mg
$ 45.00

Crysdot
tert-Butyl((1-benzyl-4-methylpiperidin-4-yl)methyl)carbamate 95+%
5g
$ 2902.00

Crysdot
tert-Butyl((1-benzyl-4-methylpiperidin-4-yl)methyl)carbamate 95+%
1g
$ 967.00

AK Scientific
tert-butylN-[(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate
250mg
$ 545.60

Total 2 raw suppliers

Chemical Property of tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Chemical Property:

PSA：41.57000
LogP:4.14220

Purity/Quality:

99% ^*data from raw suppliers

tert-butylN-[(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

There total 4 articles about tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 62718-32-5
1-benzyl-4-methyl-piperidine-4-carbonitrile

: 1345728-58-6
tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Guidance literature:: di-tert-butyl dicarbonate; 1-benzyl-4-methyl-piperidine-4-carbonitrile; With nickel(II) chloride hexahydrate; In methanol; at 20 ℃; for 0.25h;

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 8h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1345728-53-1
1-(1-benzyl-4-methylpiperidin-4-yl)methylamine

: 1345728-58-6
tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

: 100-44-7
benzyl chloride

: 1345728-58-6
tert-butyl [(1-benzyl-4-methylpiperidin-4-yl)methyl]carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / 50 °C / Cooling with ice; Inert atmosphere

3: tetrahydrofuran / 16 h / 20 °C

With lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;