3-Bromo-4-methylbenzylamine

Base Information

Chemical Name:3-Bromo-4-methylbenzylamine
CAS No.:1177558-32-5
Molecular Formula:C₈H₁₀BrN
Molecular Weight:200.078
Hs Code.:
European Community (EC) Number:861-404-8

Synonyms:3-Bromo-4-methylbenzylamine;1177558-32-5;(3-BROMO-4-METHYLPHENYL)METHANAMINE;SCHEMBL1363463;GDRGOJWXIJAVCR-UHFFFAOYSA-N;(3-bromo-4-methylphenyl)methylamine;AC7764;MFCD18392011;AKOS016000011;[(3-bromo-4-methylphenyl)methyl]amine;1-(3-bromo-4-methylphenyl)methanamine;SB78115;SY028613;CS-0309329;FT-0716400;EN300-175560;A925611;A1-01528

Suppliers and Price of 3-Bromo-4-methylbenzylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Bromo-4-methylbenzylamine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:198.99966
Heavy Atom Count:10
Complexity:105

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)CN)Br

Technology Process of 3-Bromo-4-methylbenzylamine

There total 4 articles about 3-Bromo-4-methylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 42872-74-2
3-bromo-4-methyl-benzonitrile

: 1177558-32-5
(3-bromo-4-methylphenyl)methanamine

Guidance literature:: With ammonia; hydrogen; In toluene; at 120 ℃; for 16h; under 22502.3 Torr; Autoclave;
DOI:10.1039/c8sc02807a

Reference yield:

: 183723-09-3
3-bromo-4-methyl-benzamide

: 1177558-32-5
(3-bromo-4-methylphenyl)methanamine

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 60 ℃;

Reference yield:

: 7697-26-9
3-bromo-4-methylbenzoic acid

: 1177558-32-5
(3-bromo-4-methylphenyl)methanamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 48 h / 20 °C / Inert atmosphere

2.1: ammonium hydroxide / ethyl acetate / 0.5 h

3.1: dimethylsulfide borane complex / tetrahydrofuran / 136 h / 0 - 60 °C

3.2: 4 h / 50 °C / pH 2

3.3: pH 10

With ammonium hydroxide; oxalyl dichloride; dimethylsulfide borane complex; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; ethyl acetate;