5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

Base Information

Chemical Name:5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine
CAS No.:911115-16-7
Molecular Formula:C₂₁H₁₁F₆N₅
Molecular Weight:447.342
Hs Code.:

Synonyms:5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine;Decoglurant

Suppliers and Price of 5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 16 raw suppliers

Chemical Property of 5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

There total 16 articles about 5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 82454-61-3
5-(ethynyl)pyridine-2-amine

: 911112-17-9
C₁₄H₆F₆IN₃

: 911115-16-7
5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-y1]ethynyl]-2-pyridinamine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In 2-methyltetrahydrofuran; at 70 - 75 ℃;

Reference yield: 83.0%

: 911112-17-9
C₁₄H₆F₆IN₃

: 911114-11-9
C₁₀H₁₂N₂O

: 911115-16-7
5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-y1]ethynyl]-2-pyridinamine

Guidance literature:: C₁₀H₁₂N₂O; With sodium carbonate; sodium hydroxide; In toluene; at 100 - 105 ℃; under 600.06 Torr;

C₁₄H₆F₆IN₃; With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine; In 2-methyltetrahydrofuran; at 70 - 75 ℃;