5-Acetyl-nicotinamide

Base Information

• Chemical Name: 5-Acetyl-nicotinamide
• CAS No.: 59936-03-7
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.164
• Mol file: 59936-03-7.mol

Synonyms:5-Acetyl-nicotinamide

Chemical Property of 5-Acetyl-nicotinamide

Chemical Property:

• PSA: 73.05000
• LogP: 1.08340

Purity/Quality:

97% ^*data from raw suppliers

5-acetyl-3-Pyridinecarboxamide 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Acetyl-nicotinamide

There total 2 articles about 5-Acetyl-nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

5-bromonicotinamide (28733-43-9) + tributyl(1-ethoxyvinyl)stannane (97674-02-7) → 5-Acetylpyridin-3-carboxamid (59936-03-7)

Guidance literature:

bis-triphenylphosphine-palladium(II) chloride; In toluene; for 3h; Heating / reflux;

Reference yield: 78.0%

→ 5-Acetylpyridin-3-carboxamid (59936-03-7)

Guidance literature:

upstream raw materials:

5-bromonicotinamide

tributyl(1-ethoxyvinyl)stannane

Refernces

• 1、 -. "Kinase inhibitors". Page/Page column 24. . Retrieved 2010/01/31.