5-Tert-butyl-4-(chloromethyl)-2-furamide

Base Information

Chemical Name:5-Tert-butyl-4-(chloromethyl)-2-furamide
CAS No.:634171-67-8
Molecular Formula:C₁₀H₁₄ClNO₂
Molecular Weight:215.68
Hs Code.:
DSSTox Substance ID:DTXSID00363980
Wikidata:Q82147738

Synonyms:5-TERT-BUTYL-4-(CHLOROMETHYL)-2-FURAMIDE;634171-67-8;5-tert-butyl-4-(chloromethyl)furan-2-carboxamide;5-(tert-Butyl)-4-(chloromethyl)furan-2-carboxamide;SCHEMBL23044588;DTXSID00363980;MFCD03765260;AKOS006223425;4-chloromethyl-5-t-butylfurancarboxamide;BS-38366;5-tert-Butyl-4-chloromethyl-furan-2-carboxylic acid amide

Suppliers and Price of 5-Tert-butyl-4-(chloromethyl)-2-furamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-Tert-butyl-4-(chloromethyl)-2-furamide

Chemical Property:

Vapor Pressure:0.00254mmHg at 25°C
Boiling Point:287.1°C at 760 mmHg
Flash Point:127.4°C
Density:1.163g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:215.0713064
Heavy Atom Count:14
Complexity:225

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=C(C=C(O1)C(=O)N)CCl

Technology Process of 5-Tert-butyl-4-(chloromethyl)-2-furamide

There total 5 articles about 5-Tert-butyl-4-(chloromethyl)-2-furamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 701216-63-9
4-chloromethyl-5-tert-butylfuran-2-carboxylic acid chloride

: 634171-67-8
4-chloromethyl-5-tert-butylfuran-2-carboxamide

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; water; cooling;
DOI:10.1023/B:RUGC.0000018647.14195.32

Reference yield:

: 701216-59-3
methyl 4-chloromethyl-5-tert-butylfuran-2-carboxylate

: 634171-67-8
4-chloromethyl-5-tert-butylfuran-2-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / acetic acid / 13 h / 130 °C

2: 5.2 g / KOH / H₂O / 6 h / Heating

3: 10.5 g / thionyl chloride / benzene / 6 h / Heating

4: 4 g / aq.NH₃ / dioxane; H₂O / cooling

With potassium hydroxide; ammonium hydroxide; thionyl chloride; acetic acid; In 1,4-dioxane; water; benzene;
DOI:10.1023/B:RUGC.0000018647.14195.32

Reference yield:

: 262361-64-8
methyl 4-acetoxymethyl-5-tert-butylfuran-2-carboxylate

: 634171-67-8
4-chloromethyl-5-tert-butylfuran-2-carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 5.2 g / KOH / H₂O / 6 h / Heating

2: 10.5 g / thionyl chloride / benzene / 6 h / Heating

3: 4 g / aq.NH₃ / dioxane; H₂O / cooling

With potassium hydroxide; ammonium hydroxide; thionyl chloride; In 1,4-dioxane; water; benzene;
DOI:10.1023/B:RUGC.0000018647.14195.32