(2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID

Base Information

• Chemical Name: (2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID
• CAS No.: 110078-81-4
• Molecular Formula: C12H12ClNO3S
• Molecular Weight: 285.75

Synonyms:(2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID;(2R,4R)-3-acetyl-2-(4-chlorophenyl)-1,3-thiazolidine-4-carboxylic acid;4-thiazolidinecarboxylic acid, 3-acetyl-2-(4-chlorophenyl);(2R,4R)-2-(4-chlorophenyl)-3-ethanoyl-1,3-thiazolidine-4-carboxylic acid;(2R,4R)-3-acetyl-2-(4-chlorophenyl)-4-thiazolidinecarboxylic acid

Chemical Property of (2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID

Chemical Property:

• PSA: 82.91000
• LogP: 2.32500

Purity/Quality:

97% ^*data from raw suppliers

(2R,4R)-3-Acetyl-2-(4-chlorophenyl)-1,3-thiazolidine-4-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID

There total 2 articles about (2R,4R)-3-ACETYL-2-(4-CHLORO-PHENYL)-THIAZOLIDINE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(4R)-2-(4-chlorophenyl)thiazolidine-4-carboxylic acid (198991-78-5) + acetic anhydride (108-24-7) → (2R,4R)-3-Acetyl-2-(4-chloro-phenyl)-thiazolidine-4-carboxylic acid (110078-81-4)

Guidance literature:

In water; at 95 - 100 ℃; for 0.0833333h;

Reference yield:

4-chlorobenzaldehyde (104-88-1) → (2R,4R)-3-Acetyl-2-(4-chloro-phenyl)-thiazolidine-4-carboxylic acid (110078-81-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / H₂O; methanol

2: 80 percent / H₂O / 0.08 h / 95 - 100 °C

In methanol; water;

upstream raw materials:

(4R)-2-(4-chlorophenyl)thiazolidine-4-carboxylic acid

acetic anhydride

4-chlorobenzaldehyde

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