2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione

Base Information

• Chemical Name: 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione
• CAS No.: 948996-03-0
• Molecular Formula: C₁₃H₈ClN₃O₂
• Molecular Weight: 273.678
• Hs Code.: 2933990090
• Mol file: 948996-03-0.mol

Synonyms:2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione

Chemical Property of 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione

Chemical Property:

• PSA: 63.16000
• LogP: 1.86410
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-((6-Chloropyridazin-3-yl)methyl)isoindoline-1,3-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione

There total 2 articles about 2-((6-Chloropyridazin-3-yl)Methyl)isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

potassium phtalimide (1074-82-4) + 3-chloro-6-pyridazinyl methyl chloride (120276-59-7) → C13H8ClN3O2 (948996-03-0)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.1021/jf072851x

Reference yield: 50.0%

3-chloro-6-methylpyridazine (1121-79-5) + N-bromophthalimide (2439-85-2) → C13H8ClN3O2 (948996-03-0)

Guidance literature:

With copper(l) iodide; 2,2'-azobis(isobutyronitrile); potassium carbonate; triphenylphosphine; In 1,4-dioxane; at 120 ℃; for 24h; Inert atmosphere;

Reference yield:

C13H8ClN3O2 (948996-03-0) → (6-chloropyridazin-3-yl)methanamine (871826-15-2)

Guidance literature:

With hydrazine hydrate; In ethanol; for 5h; Reflux;

DOI:10.1021/jf072851x

upstream raw materials:

potassium phtalimide

3-chloro-6-pyridazinyl methyl chloride

3-chloro-6-methylpyridazine

N-bromophthalimide

Downstream raw materials:

(6-chloropyridazin-3-yl)methanamine