1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene

Base Information

Chemical Name:1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene
CAS No.:237435-43-7
Molecular Formula:C₁₄H₁₂ClN₃O
Molecular Weight:0
Hs Code.:
Mol file:237435-43-7.mol

Synonyms:1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene

Suppliers and Price of 1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene

There total 5 articles about 1-(4-Chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6-(4-methoxyphenyl)-2-methylpyrrolo [3,2-d]pyrimidine-4-ol

: 237435-43-7
1-(4-chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxy benzene

Guidance literature:: With trichlorophosphate;

Reference yield:

: 237435-42-6
6-(4-Methoxyphenyl)-2-methylpyrrolo[3,2-d]pyrimidine-4-ol

: 237435-43-7
1-(4-chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxy benzene

Guidance literature:: With trichlorophosphate; at 120 ℃; for 24h;
DOI:10.1021/jm000269t

Reference yield:

: 3672-47-7
3-oxo-3-(4'-methoxyphenyl)propanenitrile

: 237435-43-7
1-(4-chloro-2-methylpyrrolo[4,5-d]pyrimidin-6-yl)-4-methoxy benzene

Guidance literature:: Multi-step reaction with 4 steps

1.1: Et₃N / CH₂Cl₂ / 23 h / 0 - 22 °C

2.1: NaOEt / ethanol / 2 h / 20 °C

3.1: HCl gas / 20 °C

3.2: 6percent aq. NaOH / ethanol / 6 h / Heating

4.1: POCl₃ / 24 h / 120 °C

With hydrogenchloride; sodium ethanolate; triethylamine; trichlorophosphate; In ethanol; dichloromethane;
DOI:10.1021/jm000269t