N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide

Base Information

• Chemical Name: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide
• CAS No.: 927822-86-4
• Molecular Formula: C16H16Cl4N2O4S4
• Molecular Weight: 570.38124
• Mol file: 927822-86-4.mol

Synonyms:N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide;KC7F2;N,N'-(2,2'-disulfanediylbis(ethane-2,1-diyl))bis(2,5-dichlorobenzenesulfonamide)

Chemical Property of N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonaMide

Chemical Property:

• Boiling Point: 708.8±70.0 °C(Predicted)
• PKA: 9.26±0.50(Predicted)
• PSA: 159.70000
• Density: 1.583±0.06 g/cm3(Predicted)
• LogP: 7.88180
• Storage Temp.: ?20°C
• Solubility.: DMSO: soluble20mg/mL, clear

Purity/Quality:

99% ^*data from raw suppliers

KC7F2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: KC7F2 (927822-86-4) is an inhibitor of HIF-1α (IC50 = 20 μM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.
• Uses: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide is a hypoxia inducible factor (HIF-1) inhibitor which act via down regulation of HIF-1α synthesis. N,N''-(Dithiodi-2,1-ethanediyl)bis[2,5-dichloro-benzenesulfonamide is a hypoxia inducible factor (HIF-1) inhibitor which act via down regulation of HIF-1α synthesis.