4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester

Base Information

• Chemical Name: 4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester
• CAS No.: 174884-21-0
• Molecular Formula: C15H20O5
• Molecular Weight: 280.321
• Mol file: 174884-21-0.mol

Synonyms:4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester

Chemical Property of 4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester

Chemical Property:

• PSA: 61.83000
• LogP: 2.61990
• Solubility.: Chloroform, Dichloromethane, Dimethyl Formamide

Purity/Quality:

4-(4-Acetyl-2-methoxyphenoxy)-butanoicAcidEthylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A photolabile linker for the solid-phase synthesis of 4-substituted 1,2,3-triazoles.

Technology Process of 4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester

There total 2 articles about 4-(4-Acetyl-2-Methoxyphenoxy)-butanoic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Ethyl 4-bromobutyrate (2969-81-5) + 1-(3-methoxy-4-hydroxyphenyl)ethanone (498-02-2) → ethyl 4-(4-acetyl-2-methoxyphenoxy) butanoate (174884-21-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 50 ℃; for 19h;

DOI:10.1039/c0cc05274d

Reference yield:

→ ethyl 4-(4-acetyl-2-methoxyphenoxy) butanoate (174884-21-0)

Guidance literature:

Reference yield: 98.0%

pyrene-1-aldehyde (3029-19-4) + ethyl 4-(4-acetyl-2-methoxyphenoxy) butanoate (174884-21-0) → (E)-4-(2-methoxy-4-(3-(pyren-1-yl)acryloyl)phenoxy)butanoic acid

Guidance literature:

With water; sodium hydroxide; In ethanol; at 20 ℃; Inert atmosphere; Darkness;

DOI:10.1002/anie.202003130

upstream raw materials:

Ethyl 4-bromobutyrate

1-(3-methoxy-4-hydroxyphenyl)ethanone

Downstream raw materials:

4-[4-(1-Hydroxy-ethyl)-2-methoxy-phenoxy]-butyric acid ethyl ester

4-[4-(1-hydroxyethyl)-2-methoxy-5-nitrophenoxy]butanoic acid

4-(4-Acetylphenyloxy)butyric acid

ethyl 4-(4-acetyl-2-methoxy-5-nitrophenoxy)butanoate