(R)-tert-Butyl (3-methylbutan-2-yl)carbamate

Base Information

Chemical Name:(R)-tert-Butyl (3-methylbutan-2-yl)carbamate
CAS No.:293305-73-4
Molecular Formula:C₁₀H₂₁NO₂
Molecular Weight:187.282
Hs Code.:
DSSTox Substance ID:DTXSID401165542
Nikkaji Number:J1.413.147G
Mol file:293305-73-4.mol

Synonyms:293305-73-4;(R)-tert-Butyl (3-methylbutan-2-yl)carbamate;SCHEMBL7889210;DTXSID401165542;(R)-tert-Butyl(3-methylbutan-2-yl)carbamate;[(R)-1,2-Dimethylpropyl]carbamic acid tert-butyl ester;Carbamic acid, [(1R)-1,2-dimethylpropyl]-, 1,1-dimethylethyl ester

Suppliers and Price of (R)-tert-Butyl (3-methylbutan-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-tert-Butyl(3-methylbutan-2-yl)carbamate 95+%
1g
$ 412.00

Total 1 raw suppliers

Chemical Property of (R)-tert-Butyl (3-methylbutan-2-yl)carbamate

Chemical Property:

Melting Point:35 - 36 °C
PSA：38.33000
LogP:2.94650
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:187.157228913
Heavy Atom Count:13
Complexity:170

Purity/Quality:: (R)-tert-Butyl(3-methylbutan-2-yl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(C)NC(=O)OC(C)(C)C
Isomeric SMILES:C[C@H](C(C)C)NC(=O)OC(C)(C)C

Technology Process of (R)-tert-Butyl (3-methylbutan-2-yl)carbamate

There total 4 articles about (R)-tert-Butyl (3-methylbutan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 161529-21-1
(S)-(1-iodomethyl-2-methylpropyl)carbamic acid tert-butyl ester

: 293305-73-4
tert-butyl (1R)-1,2-dimethylpropyl carbamate

Guidance literature:: With sodium tri-sec-butylborohydride; In tetrahydrofuran; at 5 ℃; for 1.5h;
DOI:10.1021/jo000242h

Reference yield:

: 2026-48-4,473-75-6
(S)-valinol

: 293305-73-4
tert-butyl (1R)-1,2-dimethylpropyl carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / CHCl₃ / 0 - 20 °C

2: 88 percent / iodine; triphenylphosphine polystyryl-supported; imidazole / CH₂Cl₂ / 2 h / Heating

3: 92 percent / N-Selectride / tetrahydrofuran / 1.5 h / 5 °C

With 1H-imidazole; triphenylphosphine polystyryl-supported; iodine; sodium tri-sec-butylborohydride; In tetrahydrofuran; dichloromethane; chloroform; 1: Substitution / 2: Substitution / 3: Reduction;
DOI:10.1021/jo000242h

Reference yield:

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 293305-73-4
tert-butyl (1R)-1,2-dimethylpropyl carbamate

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / lithium borohydride; trimethylsilyl chloride / tetrahydrofuran / 0.25 h / 20 °C

2: 99 percent / CHCl₃ / 0 - 20 °C

3: 88 percent / iodine; triphenylphosphine polystyryl-supported; imidazole / CH₂Cl₂ / 2 h / Heating

4: 92 percent / N-Selectride / tetrahydrofuran / 1.5 h / 5 °C

With 1H-imidazole; lithium borohydride; chloro-trimethyl-silane; triphenylphosphine polystyryl-supported; iodine; sodium tri-sec-butylborohydride; In tetrahydrofuran; dichloromethane; chloroform; 1: Reduction / 2: Substitution / 3: Substitution / 4: Reduction;
DOI:10.1021/jo000242h