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6,12-Di-O-methylerythromycin

Base Information
  • Chemical Name:6,12-Di-O-methylerythromycin
  • CAS No.:128940-83-0
  • Molecular Formula:C39H71NO13
  • Molecular Weight:761.992
  • Hs Code.:
  • UNII:5MB8Z3G5B8
  • DSSTox Substance ID:DTXSID90561938
  • Nikkaji Number:J1.662.287G
  • Wikidata:Q82445875
  • Mol file:128940-83-0.mol
6,12-Di-O-methylerythromycin

Synonyms:128940-83-0;(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12-hydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7,13-dimethoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;6,12-Di-O-methylerythromycin;12-O-Methylclarithromycin;12-O-Methyl Clarithromycin (~90%);6,12-Di-O-methylerythromycin A;Clarithromycin Impurity F;5MB8Z3G5B8;DTXSID90561938;PUBCHEM_14589671;Erythromycin, 6,12-di-O-methyl-

Suppliers and Price of 6,12-Di-O-methylerythromycin
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • 12-O-Methyl Clarithromycin
  • 10mg
  • $ 460.00
  • TRC
  • 12-O-MethylClarithromycin(>90%)
  • 10mg
  • $ 685.00
  • Medical Isotopes, Inc.
  • 12-O-MethylClarithromycin
  • 2.5 mg
  • $ 490.00
  • Biosynth Carbosynth
  • Clarithromycin impurity F
  • 25 mg
  • $ 1700.00
  • Biosynth Carbosynth
  • Clarithromycin impurity F
  • 10 mg
  • $ 1100.00
  • Biosynth Carbosynth
  • Clarithromycin impurity F
  • 1 mg
  • $ 300.00
Total 16 raw suppliers
Chemical Property of 6,12-Di-O-methylerythromycin
Chemical Property:
  • Melting Point:112-115 °C 
  • Boiling Point:806.1±65.0 °C(Predicted) 
  • PKA:13.19±0.70(Predicted) 
  • PSA:171.91000 
  • Density:1.16±0.1 g/cm3(Predicted) 
  • LogP:3.09380 
  • Storage Temp.:-20°C Freezer, Under inert atmosphere 
  • Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) 
  • XLogP3:3.7
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:14
  • Rotatable Bond Count:9
  • Exact Mass:761.49254132
  • Heavy Atom Count:53
  • Complexity:1210
Purity/Quality:

97% *data from raw suppliers

12-O-Methyl Clarithromycin *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)O)(C)OC
  • Isomeric SMILES:CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)OC
  • Uses 12-O-Methyl Clarithromycin is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. 12-O-Methyl Clarithromycin (Clarithromycin EP Impurity F) is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
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