(S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate

Base Information

Chemical Name:(S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate
CAS No.:149991-72-0
Molecular Formula:C₁₆H₃₁N₃O₃
Molecular Weight:313.44
Hs Code.:
Mol file:149991-72-0.mol

Synonyms:(S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate

Suppliers and Price of (S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of (S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate

Chemical Property:

Boiling Point:513.7±50.0 °C(Predicted)
PKA:12.93±0.46(Predicted)
Density:1.037±0.06 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of (S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate

There total 4 articles about (S)-tert-butyl (6-(pyrrolidine-2-carboxaMido)hexyl)carbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145428-72-4
Z-Pro-NH-(CH₂)6-NH-Boc

: 149991-72-0
{6-[((S)-Pyrrolidine-2-carbonyl)-amino]-hexyl}-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium; In methanol; for 2h;
DOI:10.1248/cpb.40.2199

Reference yield:

: 124-09-4
1,6-Hexanediamine

: 149991-72-0
{6-[((S)-Pyrrolidine-2-carbonyl)-amino]-hexyl}-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: dioxane; H₂O

2: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, 1-hydroxybenzyltriazole / dimethylformamide

3: H₂ / Pd / methanol / 2 h

With 1-hydroxybenzyltriazole; hydrogen; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium; In 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.40.2199

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 149991-72-0
{6-[((S)-Pyrrolidine-2-carbonyl)-amino]-hexyl}-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: dioxane; H₂O

2: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, 1-hydroxybenzyltriazole / dimethylformamide

3: H₂ / Pd / methanol / 2 h

With 1-hydroxybenzyltriazole; hydrogen; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium; In 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
DOI:10.1248/cpb.40.2199