[(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester

Base Information

Chemical Name:[(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester
CAS No.:83542-13-6
Molecular Formula:C₁₀H₁₈N₂O₄
Molecular Weight:230.264
Hs Code.:

Synonyms:[(2S,3S)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester;[(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester

Suppliers and Price of [(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[(2S,3S)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamicAcid1,1-DimethylethylEster
5mg
$ 140.00

TRC
[(2S,3S)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamicAcid1,1-DimethylethylEster
50mg
$ 1100.00

Medical Isotopes, Inc.
[(2S,3S)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamicAcid1,1-DimethylethylEster
5 mg
$ 625.00

Total 0 raw suppliers

Chemical Property of [(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester

Chemical Property:

PSA：71.36000
LogP:0.81410
Solubility.:Dichloromethane, Methanol

Purity/Quality:: [(2S,3S)-1-Methoxy-2-methyl-4-oxo-3-azetidinyl]-carbamicAcid1,1-DimethylethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester

There total 4 articles about [(2S-trans)-1-Methoxy-2-Methyl-4-oxo-3-azetidinyl]-carbaMic Acid 1,1-DiMethylethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 83511-28-8
Methanesulfonic acid (1R,2S)-2-tert-butoxycarbonylamino-2-methoxycarbamoyl-1-methyl-ethyl ester

: 83542-13-6
(3S)-trans-1-methoxy-3-[(tert-butoxycarbonyl)amino]-4-methyl-2-azetidinone

Guidance literature:: With potassium carbonate; In acetone; for 1h; Heating;
DOI:10.1021/jo00147a024

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 83542-13-6
(3S)-trans-1-methoxy-3-[(tert-butoxycarbonyl)amino]-4-methyl-2-azetidinone

Guidance literature:: Multi-step reaction with 4 steps

1: aq. KOH; 2-methyl-propan-2-ol / 5 h

2: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide (WSC) / pH=4.2

3: 78 percent / pyridine / 2 h / 0 °C

4: 87 percent / K₂CO₃ / acetone / 1 h / Heating

With pyridine; potassium carbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In potassium hydroxide; acetone; tert-butyl alcohol;
DOI:10.1021/jo00147a024

Reference yield:

: 2592-18-9
Boc-Thr-OH

: 83542-13-6
(3S)-trans-1-methoxy-3-[(tert-butoxycarbonyl)amino]-4-methyl-2-azetidinone

Guidance literature:: Multi-step reaction with 3 steps

1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide (WSC) / pH=4.2

2: 78 percent / pyridine / 2 h / 0 °C

3: 87 percent / K₂CO₃ / acetone / 1 h / Heating

With pyridine; potassium carbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In acetone;
DOI:10.1021/jo00147a024