3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate

Base Information

Chemical Name:3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate
CAS No.:256369-34-3
Molecular Formula:C₅H₁₀N₂*2C₇H₈O₃S
Molecular Weight:442.557
Hs Code.:
Mol file:256369-34-3.mol

Synonyms:3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate;3-Aza-Bicyclo[3.1.0]Hexan-6-AMine Bis(4-Methylbenzenesulfonic Acid) Salt

Suppliers and Price of 3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate

There total 5 articles about 3-azabicyclo[3.1.0]hexan-6-aMine 4-Methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 104-15-4
toluene-4-sulfonic acid

: 134575-17-0
tert-butyl (1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-ylcarbamate

: 256369-34-3
(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane ditosylate salt

Guidance literature:: In methanol; for 2h; Heating;
DOI:10.1039/a910340f

Reference yield:

: 151860-17-2
(1α,5α,6α)-3-N-benzyl-6-amino-3-aza-bicyclo[3.1.0]hexane

: 256369-34-3
(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane ditosylate salt

Guidance literature:: Multi-step reaction with 3 steps

1: Na₂CO₃; aq. NaOH / ethyl acetate / 3 h / 30 °C

2: 89 percent / H₂O; H₂ / 10percent Pd/C / methanol / 20 °C

3: 76 percent / methanol / 2 h / Heating

With sodium hydroxide; water; hydrogen; sodium carbonate; 10percent Pd/C; In methanol; ethyl acetate; 1: Acylation / 2: Hydrogenolysis / 3: Substitution;
DOI:10.1039/a910340f

Reference yield:

: 151860-16-1
(1α,5α,6α)-3-N-benzyl-6-nitro-3-azabicyclo[3.1.0]hexane

: 256369-34-3
(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane ditosylate salt

Guidance literature:: Multi-step reaction with 4 steps

1: H₂; H₂O / 5percent Pt/C / methanol / 24 h / 50 °C / 2660.18 Torr

2: Na₂CO₃; aq. NaOH / ethyl acetate / 3 h / 30 °C

3: 89 percent / H₂O; H₂ / 10percent Pd/C / methanol / 20 °C

4: 76 percent / methanol / 2 h / Heating

With sodium hydroxide; water; hydrogen; sodium carbonate; 5percent Pt/C; 10percent Pd/C; In methanol; ethyl acetate; 1: Reduction / 2: Acylation / 3: Hydrogenolysis / 4: Substitution;
DOI:10.1039/a910340f