(3-Formyl-2-methyl-indol-1-yl)-acetic acid

Base Information

Chemical Name:(3-Formyl-2-methyl-indol-1-yl)-acetic acid
CAS No.:432001-45-1
Molecular Formula:C₁₂H₁₁NO₃
Molecular Weight:217.224
Hs Code.:2933990090
European Community (EC) Number:863-152-4
DSSTox Substance ID:DTXSID70355579
Wikidata:Q82134569
ChEMBL ID:CHEMBL1897400
Mol file:432001-45-1.mol

Synonyms:432001-45-1;(3-Formyl-2-methyl-indol-1-yl)-acetic acid;2-(3-formyl-2-methyl-1H-indol-1-yl)acetic acid;(3-FORMYL-2-METHYL-1H-INDOL-1-YL)ACETIC ACID;2-(3-formyl-2-methylindol-1-yl)acetic acid;CHEMBL1897400;Cambridge id 6719620;Oprea1_520900;Oprea1_728574;MLS000714339;SCHEMBL23865499;DTXSID70355579;HMS2702H07;BBL025778;BDBM50451733;MFCD02909101;STL371843;AKOS000113321;BP-11002;SMR000274319;VS-08090;CS-0118100;FT-0677757;EN300-331569;2-(3-formyl-2-methyl-1H-indol-1-yl)aceticacid;Z57625183;(3-formyl-2-methyl-indol-1-yl)-acetic acid, AldrichCPR

Suppliers and Price of (3-Formyl-2-methyl-indol-1-yl)-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3-?Formyl-?2-?methyl-?indol-?1-?yl)?-?aceticAcid
5g
$ 690.00

TRC
(3-?Formyl-?2-?methyl-?indol-?1-?yl)?-?aceticAcid
250mg
$ 85.00

SynQuest Laboratories
2-(3-Formyl-2-methyl-1H-indol-1-yl)acetic acid
1 g
$ 213.00

Matrix Scientific
(3-Formyl-2-methyl-indol-1-yl)-acetic acid
500mg
$ 100.00

Matrix Scientific
(3-Formyl-2-methyl-indol-1-yl)-acetic acid
1g
$ 164.00

Crysdot
2-(3-Formyl-2-methyl-1H-indol-1-yl)aceticacid 95+%
5g
$ 466.00

Chemenu
2-(3-Formyl-2-methyl-1H-indol-1-yl)aceticacid 95%
5g
$ 440.00

ChemBridge Corporation
(3-formyl-2-methyl-1H-indol-1-yl)aceticacid 95%
5 g
$ 133.00

Alichem
2-(3-Formyl-2-methyl-1H-indol-1-yl)aceticacid
5g
$ 596.97

Alichem
2-(3-Formyl-2-methyl-1H-indol-1-yl)aceticacid
1g
$ 196.98

Total 8 raw suppliers

Chemical Property of (3-Formyl-2-methyl-indol-1-yl)-acetic acid

Chemical Property:

Vapor Pressure:1.87E-09mmHg at 25°C
Boiling Point:465.2°C at 760 mmHg
Flash Point:235.2°C
PSA：59.30000
Density:1.27g/cm³
LogP:1.84680
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:292

Purity/Quality:

97% ^*data from raw suppliers

(3-?Formyl-?2-?methyl-?indol-?1-?yl)?-?aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=CC=CC=C2N1CC(=O)O)C=O
Uses (3-?Formyl-?2-?methyl-?indol-?1-?yl)?-?acetic Acid is a reagent used in the preparation of heterocyclic compounds acting as tyrosine kinase modulators.

Technology Process of (3-Formyl-2-methyl-indol-1-yl)-acetic acid

There total 3 articles about (3-Formyl-2-methyl-indol-1-yl)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-20-5
2-methyl-1H-indole

: 432001-45-1
(3-formyl-2-methyl-1H-indol-1-yl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / 1 h / 35 °C

2: 50percent NaH / dimethylformamide; benzene / 4 h / Ambient temperature

3: 0.2N KOH/ CH₃OH / 0.5 h / Heating

With methanol; potassium hydroxide; sodium hydride; trichlorophosphate; In N,N-dimethyl-formamide; benzene;
DOI:10.1016/0223-5234(89)90108-6

Reference yield:

: 5416-80-8
2-methyl-1H-indole-3-carbaldehyde

: 432001-45-1
(3-formyl-2-methyl-1H-indol-1-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 50percent NaH / dimethylformamide; benzene / 4 h / Ambient temperature

2: 0.2N KOH/ CH₃OH / 0.5 h / Heating

With methanol; potassium hydroxide; sodium hydride; In N,N-dimethyl-formamide; benzene;
DOI:10.1016/0223-5234(89)90108-6