Fedovapagon

Base Information

Chemical Name:Fedovapagon
CAS No.:347887-36-9
Molecular Formula:C27H34N4O3
Molecular Weight:462.592
Hs Code.:
European Community (EC) Number:680-253-7
UNII:VX2GBO4I0V
DSSTox Substance ID:DTXSID40188331
Wikidata:Q27292062
NCI Thesaurus Code:C169975
Pharos Ligand ID:XSDVQM1A6ZX2
Metabolomics Workbench ID:152840
ChEMBL ID:CHEMBL518043
Mol file:347887-36-9.mol

Synonyms:Fedovapagon;347887-36-9;Fedovapagon [INN];UNII-VX2GBO4I0V;VX2GBO4I0V;(S)-N2,N2-dimethyl-N1-(2-methyl-4-(2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)benzyl)pyrrolidine-1,2-dicarboxamide;VA-106483;CHEMBL518043;(2S)-N2,N2-dimethyl-N1-((2-Methyl-4-(2,3,4,5-tetrahydro-1H-1-benzazepine-1-carbonyl)phenyl)methyl)pyrrolidine-1,2-dicarboxamide;1,2-Pyrrolidinedicarboxamide, N2,N2-dimethyl-N1-((2-methyl-4-((2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl)phenyl)methyl)-, (2S)-;D06VWL;FEDOVAPAGON [WHO-DD];SCHEMBL2547119;DTXSID40188331;XNA88736;BDBM50246575;AKOS040741722;DB11734;NCGC00386702-01;(2S)-2-N,2-N-dimethyl-1-N-[[2-methyl-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]methyl]pyrrolidine-1,2-dicarboxamide;HY-14887;MS-28508;CS-0003613;E74592;Q27292062;(2S)-N(sup 2),N(sup 2)-Dimethyl-N(sup 1)-((2-methyl-4-(2,3,4,5-tetrahydro-1H-1-benzazepine-1-carbonyl)phenyl)methyl)pyrrolidine-1,2-dicarboxamide;1-(2-Methyl-4-(2,3,4,5-tetrahydro-1-benzazepin-1-ylcarbonyl)benzylcarbamoyl)-L-proline-N,N-dimethylamide

Suppliers and Price of Fedovapagon

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Fedovapagon
1g
$ 1320.00

ChemScene
Fedovapagon 99.03%
10mg
$ 220.00

ChemScene
Fedovapagon 99.03%
5mg
$ 140.00

ChemScene
Fedovapagon 99.03%
50mg
$ 850.00

American Custom Chemicals Corporation
FEDOVAPAGON 95.00%
5MG
$ 320.10

Total 10 raw suppliers

Chemical Property of Fedovapagon

Chemical Property:

Boiling Point:740.0±60.0 °C(Predicted)
PSA：76.45000
Density:1.203±0.06 g/cm3(Predicted)
LogP:3.94760
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:462.26309096
Heavy Atom Count:34
Complexity:741

Purity/Quality:

97% ^*data from raw suppliers

Fedovapagon ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)C(=O)N2CCCCC3=CC=CC=C32)CNC(=O)N4CCCC4C(=O)N(C)C
Isomeric SMILES:CC1=C(C=CC(=C1)C(=O)N2CCCCC3=CC=CC=C32)CNC(=O)N4CCC[C@H]4C(=O)N(C)C
Recent ClinicalTrials:Efficacy Study of Fedovapagon for Nocturia in Men With Benign Prostatic Hyperplasia (BPH)
Recent EU Clinical Trials:The PEACE Study: Investigating the Pharmacodynamics and Pharmacokinetics of FE 106483 Tablets in a Single Dose Study in Children with Nocturnal Enuresis. A Randomised, Double-Blind and Placebo-Controlled Study.
Uses Fedovapagon is a potent, nonpeptidic vasopressin V2 receptor agonists.

Technology Process of Fedovapagon

There total 2 articles about Fedovapagon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: