Quinoline-2-carboximidamide hydrochloride

Base Information

• Chemical Name: Quinoline-2-carboximidamide hydrochloride
• CAS No.: 110177-05-4
• Molecular Formula: C₁₀H₉N₃*ClH
• Molecular Weight: 207.662
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID60575784
• Mol file: 110177-05-4.mol

Synonyms:quinoline-2-carboximidamide hydrochloride;110177-05-4;quinoline-2-carboximidamide HCl;quinoline-2-carboximidamide;hydrochloride;MFCD08752296;quinoline-2-carboxamidine hcl;SCHEMBL5729637;AMY4332;DTXSID60575784;AKOS015847516;quinoline-2-carboximidamidehydrochloride;SY109191;CS-0038294;EN300-736759;W12202;A894927;Quinoline-2-carboximidamide--hydrogen chloride (1/1);Z2936474423

Chemical Property of Quinoline-2-carboximidamide hydrochloride

Chemical Property:

• PSA: 62.76000
• LogP: 3.12090
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 207.0563250
• Heavy Atom Count: 14
• Complexity: 202

Purity/Quality:

98%min ^*data from raw suppliers

Quinoline-2-carboximidamideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=N2)C(=N)N.Cl

Technology Process of Quinoline-2-carboximidamide hydrochloride

There total 1 articles about Quinoline-2-carboximidamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinoline-2-carbonitrile (1436-43-7) → quinoline-2-carboxamidine; hydrochloride (110177-05-4)

Guidance literature:

quinoline-2-carbonitrile; With methanol; sodium methylate; at 20 ℃; for 6h; Inert atmosphere;

With ammonium chloride; In methanol; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1016/j.bmc.2008.11.016

Reference yield:

diethyl (2,4,6-trifluoro-phenyl)-malonate (262609-07-4) + quinoline-2-carboxamidine; hydrochloride (110177-05-4) → C19H10F3N3O2

Guidance literature:

With tributyl-amine; at 180 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.bmc.2008.11.016

upstream raw materials:

quinoline-2-carbonitrile

Refernces