2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile

Base Information

Chemical Name:2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile
CAS No.:1226997-50-7
Molecular Formula:C₁₃H₁₅NO₂
Molecular Weight:217.268
Hs Code.:
Mol file:1226997-50-7.mol

Synonyms:2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of 2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile

There total 1 articles about 2-(4-hydroxy-tetrahydro-2H-pyran-4-yl)-2-phenylacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 140-29-4
phenylacetonitrile

: 1226997-50-7
(4-hydroxytetrahydro-2H-pyran-4-yl)(phenyl)acetonitrile

Guidance literature:: phenylacetonitrile; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 ℃; for 0.833333h;

Tetrahydro-4H-pyran-4-one; In tetrahydrofuran; hexanes; at -78 ℃; for 3.33333h;

With water; ammonium chloride; In tetrahydrofuran; hexanes; Cooling with ice;