Mepiprazole

Base Information

• Chemical Name: Mepiprazole
• CAS No.: 20326-12-9
• Molecular Formula: C16H21 Cl N4
• Molecular Weight: 304.823
• Hs Code.: 2933990090
• UNII: 977BAL0NR7
• DSSTox Substance ID: DTXSID30174223
• Nikkaji Number: J10.949E
• Wikipedia: Mepiprazole
• Wikidata: Q6817816
• NCI Thesaurus Code: C66092
• Metabolomics Workbench ID: 152232
• ChEMBL ID: CHEMBL2106537
• Mol file: 20326-12-9.mol

Synonyms:1-(3-chlorophenyl)-4-(2-(5-methylpyrazol- 3-yl)ethyl)piperazine dihydrochloride;EMD 16,923;mepiprazole;mepiprazole dihydrochloride;Quiadon

Chemical Property of Mepiprazole

Chemical Property:

• Vapor Pressure: 5.98E-10mmHg at 25°C
• Melting Point: 106°
• Boiling Point: 495.3°Cat760mmHg
• PKA: 15.10±0.10(Predicted)
• Flash Point: 253.3°C
• PSA: 35.16000
• Density: 1.215g/cm³
• LogP: 2.73910
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 304.1454744
• Heavy Atom Count: 21
• Complexity: 319

Purity/Quality:

98% ^*data from raw suppliers

MEPIPRAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NN1)CCN2CCN(CC2)C3=CC(=CC=C3)Cl

Technology Process of Mepiprazole

There total 1 articles about Mepiprazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-(3-chloro-phenyl)-4-[2-(5-methyl-1(2)H-pyrazol-3-yl)-ethyl]-piperazine (20326-12-9)

Guidance literature:

entspr. 2-Pyrazolin, SO2Cl2 bzw. Cl2; Br2; MnO2; Hg(OAc)2; NaOCl; K2Cr2O7; H2O2, Pb(OAc)4; Chloranil; Pd; Pt+O2; PdCl2, NaNHNH2+N2H4; Ce-(IV)-Salze; KMnO4; NBS;

Refernces

• 1、 Poetsch,Koppe. "Substituted 4 phenyl 1 (3 pyrazolyl alkyl) piperazines. II. Synthesis of 3 pyrazolyl ethylamines". . p. 162 - 170. Retrieved 2007/10/05.