ThioFluor 623

Base Information

• Chemical Name: ThioFluor 623
• CAS No.: 1004324-99-5
• Molecular Formula: C31H37N6O10S
• Molecular Weight: 678.679
• Mol file: 1004324-99-5.mol

Synonyms:ThioFluor 623

Chemical Property of ThioFluor 623

Chemical Property:

• PSA: 260.06000
• LogP: 6.63760

Purity/Quality:

≥98% ^*data from raw suppliers

ThioFluor623 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Thiofluor 623 responds upon exposure to thiols with an increase in fluorescence intensity of up to 120-fold. The response is selective for thiols and occurs in aqueous media. In the absence of thiols, the probe is essentially non-fluorescent; thiols cause cleavage of the probe, making a fluorophore with an absorption maximum of 563 nm and emission at 623 nm. The fluorescence quantum yield of the cleaved product, generated in response to thiols, increases in more viscous media, suggesting ideal performance in biological systems and applicability to single-molecule or 2-photon sensing schemes. The thiofluor 623 is cell-permeable and reacts selectively with intracellular thiols.

Technology Process of ThioFluor 623

There total 1 articles about ThioFluor 623 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

N-(4-formylphenyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-2,4-dinitrobenzenesulfonamide (1004324-98-4) + 2-dicyanomethylidene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (171082-32-9) → (E)-N-(4-(2-(4-cyano-5-dicyanomethylene-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)phenyl)-N-(4-formylphenyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-2,4-dinitrobenzenesulfonamide (1004324-99-5)

Guidance literature:

With ammonium acetate; In tetrahydrofuran; ethanol; at 20 ℃;

DOI:10.1021/ol702539v

Reference yield: 82.0%

(E)-N-(4-(2-(4-cyano-5-dicyanomethylene-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)phenyl)-N-(4-formylphenyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-2,4-dinitrobenzenesulfonamide (1004324-99-5) → (E)-(2-(3-cyano-4-(2-(2-(2-methoxyethoxy)ethoxy)ethylamino)styryl)-5,5-dimethylfuran-2(5H)-ylidene)propane-1,3-dinitrile (1004325-00-1)

Guidance literature:

With rac-cysteine; triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1021/ol702539v

upstream raw materials:

N-(4-formylphenyl)-N-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-2,4-dinitrobenzenesulfonamide

2-dicyanomethylidene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran

Downstream raw materials:

(E)-(2-(3-cyano-4-(2-(2-(2-methoxyethoxy)ethoxy)ethylamino)styryl)-5,5-dimethylfuran-2(5H)-ylidene)propane-1,3-dinitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1004324-99-5 ThioFluor 623

Send

Send

Metric Ton KG G Pound L ML

Send

Send