DL-Leucine-2-13C

Base Information

• Chemical Name: DL-Leucine-2-13C
• CAS No.: 65792-32-7
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 132.164
• DSSTox Substance ID: DTXSID60514734
• Mol file: 65792-32-7.mol

Synonyms:DL-Leucine-2-13C;65792-32-7;2-amino-4-methyl(213C)pentanoic acid;( inverted exclamation markA)-Leucine-13C;(2-~13~C)Leucine;DTXSID60514734;HY-B1674S1;AKOS015913698;DL-Leucine-2-13C, 99 atom % 13C;CS-0379517

Chemical Property of DL-Leucine-2-13C

Chemical Property:

• Melting Point: 293-296 °C (subl.)(lit.)
• PSA: 63.32000
• LogP: 1.14470
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 132.097983493
• Heavy Atom Count: 9
• Complexity: 101

Purity/Quality:

98% ^*data from raw suppliers

DL-Leucine-2-13C ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(C(=O)O)N
• Isomeric SMILES: CC(C)C[13CH](C(=O)O)N

Technology Process of DL-Leucine-2-13C

There total 1 articles about DL-Leucine-2-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanide (151-50-8) + <1-13C>-3-methyl-butanoic acid sodium salt → (2RS)-<2-13C>-leucine (65792-32-7)

Guidance literature:

With hydrogenchloride; lithium aluminium tetrahydride; ammonium chloride; ammonia; 1,1'-carbonyldiimidazole; Yield given. Multistep reaction;

Reference yield:

(2RS)-<2-13C>-leucine (65792-32-7) → paniculide B (21764-33-0,84048-30-6)

Guidance literature:

at 25 ℃; for 7h;

Reference yield:

(2RS)-<2-13C>-leucine (65792-32-7) → paniculide B (21764-33-0,84048-30-6)

Guidance literature:

With L-[U-¹⁴C]leucine; at 25 ℃; for 168h; Mechanism; mechanism of the incorporation of leucine to paniculide B;

upstream raw materials:

potassium cyanide

Downstream raw materials:

paniculide B

paniculide A