2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE

Base Information

• Chemical Name: 2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE
• CAS No.: 206559-60-6
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Hs Code.: 2926909090
• Mol file: 206559-60-6.mol

Synonyms:2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE

Chemical Property of 2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE

Chemical Property:

• Vapor Pressure: 0.000805mmHg at 25°C
• Melting Point: 77-80°C
• Boiling Point: 305.8°C at 760 mmHg
• Flash Point: 128.9°C
• PSA: 33.02000
• Density: 1.017g/cm³
• LogP: 2.37808

Purity/Quality:

98%Min ^*data from raw suppliers

2,3-Dimethyl-4-methoxyphenylacetonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE

There total 2 articles about 2,3-DIMETHYL-4-METHOXYPHENYLACETONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium cyanide (773837-37-9) + Trimethyl-<4-methoxy-2.3-dimethyl-benzyl>-ammoniumhydroxyd → (4-methoxy-2,3-dimethyl-phenyl)-acetonitrile (206559-60-6)

Guidance literature:

In ethanol; water; N,N-dimethyl-formamide; at 90 ℃; for 18h;

DOI:10.1021/jm9000242

Reference yield:

sodium cyanide (773837-37-9) + Trimethyl-<4-methoxy-2.3-dimethyl-benzyl>-ammoniumhydroxyd → (4-methoxy-2,3-dimethyl-phenyl)-acetonitrile (206559-60-6)

Guidance literature:

With 18-crown-6 ether; In N,N-dimethyl-formamide;

DOI:10.1021/jm9000242

Reference yield:

(4-methoxy-2,3-dimethyl-phenyl)-acetonitrile (206559-60-6) → 2-(4-methoxy-2,3-dimethyl-phenyl)-ethylamine (52670-15-2)

Guidance literature:

With ammonia; hydrogen; nickel; In methanol; at 20 ℃; for 36h; under 3102.97 Torr;

upstream raw materials:

sodium cyanide

Downstream raw materials:

2-(4-methoxy-2,3-dimethyl-phenyl)-ethylamine

methyl (4-methoxy-2,3-dimethylphenyl)acetate

C₁₃H₁₅NO₂

Refernces