Moexipril tert-Butyl Ester Maleic Acid Salt

Base Information

Chemical Name:Moexipril tert-Butyl Ester Maleic Acid Salt
CAS No.:103733-40-0
Molecular Formula:C35H46N2O11
Molecular Weight:554.684
Hs Code.:2933497050
Mol file:103733-40-0.mol

Synonyms:Moexipril tert-Butyl Ester Maleic Acid Salt;(2Z)-2-Butenedioate;(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-3-isoquinolinecarboxylic Acid 1,1-DiMethylethyl Ester;Moexipril Related CoMpound C;(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid 1,1-dimethylethyl ester (2Z)-2-butenedioate (1:1);Moexipril tert-butyl ester maleate

Suppliers and Price of Moexipril tert-Butyl Ester Maleic Acid Salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Moexipril tert-butyl ester maleic acid salt
5mg
$ 460.00

TRC
Moexipriltert-ButylEsterMaleicAcidSalt
25mg
$ 350.00

Total 3 raw suppliers

Chemical Property of Moexipril tert-Butyl Ester Maleic Acid Salt

Chemical Property:

Melting Point:148-150°C
PSA：178.00000
LogP:3.88200
Storage Temp.:-20?C Freezer
Solubility.:DMSO, Methanol

Purity/Quality:

99% ^*data from raw suppliers

Moexipril tert-butyl ester maleic acid salt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An impurity of Moexipril (M485350).

Technology Process of Moexipril tert-Butyl Ester Maleic Acid Salt

There total 5 articles about Moexipril tert-Butyl Ester Maleic Acid Salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32161-30-1
(S)-3,4-dimethoxyphenylalanine

: 103733-40-0
tert-butyl (S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 3 h / 90 °C / Sealed tube

2: sulfuric acid / 1,4-dioxane / 18 h / 20 °C / Sealed tube

3: dichloromethane / 1.97 h / 23 °C

With hydrogenchloride; sulfuric acid; In 1,4-dioxane; dichloromethane; water;
DOI:10.1002/chem.201904400

Reference yield:

: 76824-86-7,88980-03-4,103733-66-0
(S)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 103733-40-0
tert-butyl (S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂SO₄ / dioxane / 17 h / Ambient temperature

2: Et₃N, DCC, 1-hydroxybenzotriazole / CH₂Cl₂ / Ambient temperature

With sulfuric acid; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00160a026

Reference yield:

: 80828-26-8
N-[1-(S)-(ethoxycarbonyl)-3-phenylpropyl]-L-alanine hydrochloride

: 103733-66-0,103733-31-9
tert-butyl (S)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

: 103733-40-0
tert-butyl (S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;
DOI:10.1021/jm00160a026