(3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone

Base Information

Chemical Name:(3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone
CAS No.:94595-91-2
Molecular Formula:C₉H₁₄O₃
Molecular Weight:170.208
Hs Code.:2914400090
Mol file:94595-91-2.mol

Synonyms:(3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone

Suppliers and Price of (3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone

Chemical Property:

PSA：57.53000
LogP:-0.04520

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone

There total 13 articles about (3aS,4S,5R,6aR)-Hexahydro-5-hydroxy-4-(hydroxyMethyl)-2(1H)-pentalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26054-46-6
(-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one

: 72508-55-5,76825-42-8,94595-91-2
(-)-7-hydroxy-6(R)-hydroxymethyl-1(S),5(R)-2-oxabicyclo<3,3,0>octan-3-one

Guidance literature:: DOI:10.1016/0040-4020(80)80160-8

Reference yield:

: 70871-22-6
(1S,2R,3R,5R)-2-hydroxymethyl-3-(tetrahydropyran-2-yl)oxy-7,7-ethylenedioxybicyclo<3.3.0>octane

: 94595-91-2
(1R,5S,6S,7R)-3-oxo-6-hydroxymethyl-7-hydroxybicyclo<3.3.0>octane

Guidance literature:: With toluene-4-sulfonic acid; In water; acetone; at 40 ℃; for 2h;
DOI:10.1248/cpb.35.4000

Reference yield:

: 39746-00-4,172821-93-1
(1S,5R,6S,7R)-7-benzoyloxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one

: 94595-91-2
(1R,5S,6S,7R)-3-oxo-6-hydroxymethyl-7-hydroxybicyclo<3.3.0>octane

Guidance literature:: Multi-step reaction with 5 steps

2: 1.) Ph(Me)S(O)NMe, 2.) Al-Hg

3: 1.) LiAlH₄ / 2.) Collins oxd.

4: 30 percent / RhCl(PPh₃)3 / CH₂Cl₂ / 20 h / 40 °C

5: p-TsOH / methanol

With lithium aluminium tetrahydride; aluminium amalgam; Ph(Me)S(O)NMe; toluene-4-sulfonic acid; RhCl(PPh₃)3; In methanol; dichloromethane;