5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE

Base Information

Chemical Name:5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE
CAS No.:111869-42-2
Molecular Formula:C35H37N5O6
Molecular Weight:623.7
Hs Code.:
Mol file:111869-42-2.mol

Synonyms:5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE;5'-O-(DMT)-N2-(DMF)-7-DEAZA-2'-DEOXYGUANOSINE

Suppliers and Price of 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE 95.00%
100MG
$ 296.10

Total 6 raw suppliers

Chemical Property of 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE

Chemical Property:

PKA:11.19±0.20(Predicted)
PSA：123.43000
Density:1.29±0.1 g/cm3(Predicted)
LogP:4.62030

Purity/Quality:

97% ^*data from raw suppliers

5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE

There total 2 articles about 5'-O-(DIMETHOXYTRITYL)-N2-(DIMETHYLAMINOMETHYLIDENE)-7-DEAZA-2'-DEOXYGUANOSI NE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 111902-68-2
7-(2-Desoxy-β-D-erythro-pentofuranosyl)-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

: 111869-42-2
7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In pyridine; for 3h; Ambient temperature;

Reference yield:

: 86392-75-8
7-deaza-2'-deoxyguanosine

: 111869-42-2
7-<2-Desoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl>-2-<(dimethylamino)methylenamino>-3,7-dihydro-4H-pyrrolo<2,3-d>pyrimidin-4-on

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / dimethylformamide / 1 h / 50 °C

2: 84 percent / Huenig base / pyridine / 3 h / Ambient temperature

With N-ethyl-N,N-diisopropylamine; In pyridine; N,N-dimethyl-formamide;