(1S,2S)-2-Piperazin-1-yl-cyclohexanol

Base Information

Chemical Name:(1S,2S)-2-Piperazin-1-yl-cyclohexanol
CAS No.:936940-36-2
Molecular Formula:C₁₀H₂₀N₂O
Molecular Weight:184.282
Hs Code.:
DSSTox Substance ID:DTXSID601270674

Synonyms:(1S,2S)-2-Piperazin-1-yl-cyclohexanol;936940-36-2;(1S,2S)-2-(Piperazin-1-yl)cyclohexanol;(1S,2S)-2-piperazin-1-ylcyclohexan-1-ol;(1S,2S)-2-Piperazin-1-ylcyclohexanol;(1S,2S)-2-(piperazin-1-yl)cyclohexan-1-ol;DTXSID601270674;MFCD08445801;AKOS000558070;AKOS015854033;BB 0259698;rel-(1R,2R)-2-(1-Piperazinyl)cyclohexanol;F6545-4278

Suppliers and Price of (1S,2S)-2-Piperazin-1-yl-cyclohexanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(1S,2S)-2-Piperazin-1-yl-cyclohexanol
1g
$ 495.00

Crysdot
(1S,2S)-2-(Piperazin-1-yl)cyclohexanol 97%
5g
$ 787.00

American Custom Chemicals Corporation
(1S,2S)-2-PIPERAZIN-1-YLCYCLOHEXANOL 95.00%
1G
$ 672.00

AK Scientific
(1S,2S)-2-Piperazin-1-yl-cyclohexanol
1g
$ 718.00

Total 2 raw suppliers

Chemical Property of (1S,2S)-2-Piperazin-1-yl-cyclohexanol

Chemical Property:

PSA：35.50000
LogP:0.46180
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:184.157563266
Heavy Atom Count:13
Complexity:157

Purity/Quality:

98%min ^*data from raw suppliers

(1S,2S)-2-Piperazin-1-yl-cyclohexanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C(C1)N2CCNCC2)O
Isomeric SMILES:C1CC[C@@H]([C@H](C1)N2CCNCC2)O

Technology Process of (1S,2S)-2-Piperazin-1-yl-cyclohexanol

There total 5 articles about (1S,2S)-2-Piperazin-1-yl-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24796-87-0,5537-67-7
2-bromo-cyclohexanol

: 936940-36-2
2-piperazin-1-yl-cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; XPhos; sodium t-butanolate / toluene / 90 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; palladium diacetate; sodium t-butanolate; XPhos; In 1,4-dioxane; toluene; 1: |Buchwald-Hartwig Coupling;
DOI:10.1016/j.bmcl.2016.02.050