2-(4-Bromo-2-fluorophenyl)ethanol

Base Information

Chemical Name:2-(4-Bromo-2-fluorophenyl)ethanol
CAS No.:193290-20-9
Molecular Formula:C₈H₈BrFO
Molecular Weight:219.053
Hs Code.:
DSSTox Substance ID:DTXSID101306729
Mol file:193290-20-9.mol

Synonyms:2-(4-bromo-2-fluorophenyl)ethanol;193290-20-9;2-(4-bromo-2-fluoro-phenyl)-ethanol;SCHEMBL5826;4-Bromo-2-fluorobenzeneethanol;ATAZLKFXFGKSGH-UHFFFAOYSA-N;DTXSID101306729;AKOS013284010;2-(4-bromo-2-fluorophenyl)ethan-1-ol;BS-27460;CS-0210353;FT-0737004;EN300-1250715

Suppliers and Price of 2-(4-Bromo-2-fluorophenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-(4-Bromo-2-fluorophenyl)ethanol

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.97426
Heavy Atom Count:11
Complexity:121

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1Br)F)CCO

Technology Process of 2-(4-Bromo-2-fluorophenyl)ethanol

There total 7 articles about 2-(4-Bromo-2-fluorophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 114897-92-6
2-(4-bromo-2-fluoro-phenyl)acetic acid

: 193290-20-9
2-(4-bromo-2-fluorophenyl)ethan-1-ol

Guidance literature:: With borane-THF; In tetrahydrofuran; at -78 - 20 ℃; for 15h;
DOI:10.1002/cmdc.202000911

Reference yield:

: 114897-91-5
(4-bromo-2-fluorophenyl)acetonitrile

: 193290-20-9
2-(4-bromo-2-fluorophenyl)ethan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; water / 20 h / Reflux

2: diborane / tetrahydrofuran / 1 h / 0 - 27 °C

With hydrogenchloride; water; diborane; In tetrahydrofuran;

Reference yield:

: 4-bromo-1-(chloromethyl)-2-fluorobenzene

: 193290-20-9
2-(4-bromo-2-fluorophenyl)ethan-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: N,N-dimethyl-formamide / 18 h / 20 - 25 °C / Inert atmosphere

2: hydrogenchloride; water / 20 h / Reflux

3: diborane / tetrahydrofuran / 1 h / 0 - 27 °C

With hydrogenchloride; water; diborane; In tetrahydrofuran; N,N-dimethyl-formamide;